Lung Infections

McCullough, Ann E.; Leslie, Kevin O.

doi:10.1016/b978-0-323-44284-8.00007-7

Cited by 2 publications

(2 citation statements)

References 372 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 In immunocompetent patients, PPT affects almost exclusively the lungs and intrathoracic lymph node (LN) enlargement is rarely demonstrated in the computed tomography (CT). 2,3 Chest X-rays and CT are useful in the morphological evaluation of TB-associated changes. Positron emission tomography (PET)/CT enables assessment of the metabolic characteristics of active PPT and primary TB.…”

Section: Introductionmentioning

confidence: 99%

Comparison of 68Ga-DOTATOC and 18F-FDG Thoracic Lymph Node and Pulmonary Lesion Uptake Using PET/CT in Postprimary Tuberculosis

Rosado-de-Castro

Pereira-de-Carvalho

Barreto

et al. 2022

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Tuberculosis (TB) remains one of the world’s leading infectious cause of morbidity and mortality. Positron emission tomography (PET) associated with computed tomography (CT) allows a structural and metabolic evaluation of TB lesions, being an excellent noninvasive alternative for understanding its pathogenesis. DOTATOC labeled with gallium-68 (68Ga-DOTATOC) can bind to somatostatin receptors present in activated macrophages and lymphocytes, cells with a fundamental role in TB pathogenesis. We describe 68Ga-DOTATOC uptake distribution and patterns in thoracic lymph nodes (LN) and pulmonary lesions (PL) in immunocompetent patients with active postprimary TB, analyze the relative LN/PL uptake, and compare this two tracer’s uptake. High uptake of both radiotracers in PL and LN was demonstrated, with higher LN/PL ratio on 68Ga-DOTATOC (P < 0.05). Considering that LN in immunocompetent patients are poorly studied, 68Ga-DOTATOC can contribute to the understanding of the complex immunopathogenesis of TB.

show abstract

Section: Introductionmentioning

confidence: 99%

Comparison of 68Ga-DOTATOC and 18F-FDG Thoracic Lymph Node and Pulmonary Lesion Uptake Using PET/CT in Postprimary Tuberculosis

Rosado-de-Castro

Pereira-de-Carvalho

Barreto

et al. 2022

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

show abstract

“…It is transmitted to humans by bites from mosquitos that have sucked the blood of infected animals. Since the human is not a final host, the larvae die in the heart before maturing into adult worms and are washed out into the lungs, where they form a nidus of the thrombus in the pulmonary artery [1]. Most cases are asymptomatic and usually are noted as a lung nodule on chest X-ray or computed tomography (CT) by chance.…”

Section: Introductionmentioning

confidence: 99%

Thirteen cases of pulmonary dirofilariasis in a single institution in Okinawa Island

et al. 2019

View full text Add to dashboard Cite

Pulmonary dirofilariasis is an infection caused by Dirofilaria immitis , which is an endemic parasite in Japan. We experienced 13 surgical cases of pulmonary dirofilariasis in our hospital. Of the 13 patients, 61.5% were men. The responsible lesions were located in the right lung in all cases, and 76.9% of them were in the lower lobe. Histologically, 12 cases showed necrotic nodules with peripheral granuloma with worms inside the pulmonary artery. One case did not show a necrotic nodule but showed only thickening and hyalinization of the pulmonary artery wall with a degenerated worm inside. Eosinophils were found histologically in all cases. Thirteen cases of dirofilariasis in one institution seem to be the largest number in Japan, based on previous reports. One reason for this increased prevalence may be the hot and humid climate of our prefecture considering the ecology of the mosquito as a vector. Elastic staining and eosinophils in peripheral granulomatous areas can contribute to the diagnosis when the worms are degenerated.

show abstract

Lung Infections

Cited by 2 publications

References 372 publications

Comparison of 68Ga-DOTATOC and 18F-FDG Thoracic Lymph Node and Pulmonary Lesion Uptake Using PET/CT in Postprimary Tuberculosis

Comparison of 68Ga-DOTATOC and 18F-FDG Thoracic Lymph Node and Pulmonary Lesion Uptake Using PET/CT in Postprimary Tuberculosis

Thirteen cases of pulmonary dirofilariasis in a single institution in Okinawa Island

Contact Info

Product

Resources

About