Lung Function Testing, Spirometry, Diffusion Capacity and Interpretation

Madsen, Flemming; Mortensen, Jann; Hanel, Birgitte; Pedersen, Ole F.

doi:10.1007/978-88-470-5647-3_9

Cited by 1 publication

(1 citation statement)

References 24 publications

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“…This multicenter study was conducted from March to December 2015. Based on the spirometry guidelines from the Danish Respiratory Society, 32 participating GPs were educated in the functions of the COPD-6 (Vitalograph ® , Buckingham, UK) and spirometry procedures. The COPD-6 test was repeated three times with the highest values recorded.…”

Section: Methodsmentioning

confidence: 99%

Multicenter study of the COPD-6 screening device: feasible for early detection of chronic obstructive pulmonary disease in primary care?

Kjeldgaard¹,

Lykkegaard²,

Spillemose³

et al. 2017

COPD

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Background and aimEarly detection of COPD may reduce the future burden of the disease. We aimed to investigate whether prescreening with a COPD-6 screening device (measuring FEV1 and FEV6) facilitates early detection of COPD in primary care.MethodsIn primary care, individuals at high risk of COPD (ie, age ≥35 years, relevant exposure, and at least one respiratory symptom) and no previous diagnosis of obstructive lung disease were examined with a COPD-6 screening device. In prioritized order, the criteria for proceeding to confirmatory spirometry were FEV1/FEV6 <0.7, FEV1 <80%pred, or clinical suspicion of COPD regardless of test result (medical doctor’s [MD] decision). Based on spirometry, including bronchodilator (BD) reversibility test, individuals were classified as COPD (post-BD FEV1/FVC <0.70), asthma (ΔFEV1 ≥0.50 L), or no obstructive lung disease.ResultsA total of 2,990 subjects (54% men, mean age 59 years, and mean 28 pack-years) were enrolled, of whom 949 (32%) proceeded from COPD-6 screening to confirmative spirometry based on the following criteria: 510 (54%) FEV1/FEV6 <0.70, 382 (40%) FEV1 <80%pred, and 57 (6%) MD decision. Following confirmative spirometry, the 949 individuals were diagnosed as having COPD (51%), asthma (3%), and no obstructive lung disease (45%). COPD was diagnosed in 487 (16%) of the enrolled subjects in whom confirmative spirometry was performed in 69% based on FEV1/FEV6 <0.7 and in 29% based on FEV1 ≤80%pred.ConclusionPrescreening with the COPD-6 device showed acceptable specificity for the selection of subjects for diagnostic spirometry and is likely to be a useful alternative to current practice in primary care.

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Section: Methodsmentioning

confidence: 99%