Lung function in adult idiopathic scoliosis: a 20 year follow up.

Pehrsson, Kerstin; Bake, Björn; Larsson, Sture; Nachemson, Alf

doi:10.1136/thx.46.7.474

Cited by 143 publications

(76 citation statements)

References 16 publications

(4 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…(10,(31)(32)(33) The need for surgery should be considered when conservative treatment of AIS fails, or when there is evidence of curvature progression to a Cobb angle of 40º-50º or a large curve of 40º-50º. (33,34) Unlike AIS, surgical treatments for early-onset patients are mainly indicated early in the course of the disease to prevent highly predictable respiratory morbidity. (25) Another important factor shown in our results that may influence pulmonary function is the age of the AIS patient prior to surgery.…”

Section: Discussionmentioning

confidence: 99%

“…This is supported by a previous study which suggested that ageing was a major factor of worsening ventilatory capacity of patients with AIS, leading to a higher risk of developing respiratory failure. (34) Pulmonary reserves peak in the second decade of life and gradually decline as the patient ages. (16,35,36) Impairment in pulmonary function, which is expected with progression of scoliotic curvature, may be controlled with surgical correction.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Relationship between pulmonary function and degree of spinal deformity, location of apical vertebrae and age among adolescent idiopathic scoliosis patients

Johari¹,

Sharifudin²,

Rahman³

et al. 2016

smedj

View full text Add to dashboard Cite

RESULTSThe mean age of the patients was 16.68 ± 6.04 years. An inverse relationship was found between the degree of the Cobb angle and FVC as well as FEV1; however, the relationships were not statistically significant (p = 0.057 and p = 0.072, respectively). There was also a trend towards a significant negative correlation between the thoracic curve and FVC (p = 0.014). Patients with larger thoracic curves had lower pulmonary function. A one-year increase in age significantly decreased FVC by 1.092 units (p = 0.044). No significant relationship between age and preoperative FEV1 was found. The median FVC was significantly higher in patients with affected apical vertebrae located at levels L1-L3 than at T6-T8 or T9-T12 (p = 0.006).CONCLUSION Lung function impairment was seen in more severe spinal deformities, proximally-located curvature and older patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Relationship between pulmonary function and degree of spinal deformity, location of apical vertebrae and age among adolescent idiopathic scoliosis patients

Johari¹,

Sharifudin²,

Rahman³

et al. 2016

smedj

View full text Add to dashboard Cite

show abstract

“…1,2 When this appears, the prognosis is poor. The most disabling symptom in these patients is exercise dyspnea, which results in reduced exercise tolerance, limitation of daily life activities, and deterioration in health-related quality of life (HRQOL).…”

Section: Introductionmentioning

confidence: 99%

Pulmonary Rehabilitation Improves Exercise Capacity in Subjects with Kyphoscoliosis and Severe Respiratory Impairment

et al. 2014

View full text Add to dashboard Cite

BACKGROUND: Patients with kyphoscoliosis and severe respiratory impairment frequently experience reduction in exercise tolerance, limitation in daily life activities, and deterioration in health-related quality of life (HRQOL). Noninvasive ventilation (NIV) as an add-on treatment to long-term oxygen therapy (LTOT) was shown to improve symptoms and HRQOL in these patients. Pulmonary rehabilitation can increase exercise capacity and HRQOL in patients with COPD, but its role in patients with restrictive thoracic disease, such as kyphoscoliosis, is uncertain. The aim of this study was to analyze the effects of combining pulmonary rehabilitation with LTOT and NIV treatments on arterial blood gases and the 6-min walk test (6MWT) in a homogeneous group of subjects with kyphoscoliosis. METHODS: Twenty-three subjects with kyphoscoliosis and respiratory failure who were being treated with both LTOT and NIV and who had been referred to a pulmonary rehabilitation program were retrospectively analyzed. Eighteen subjects were included, and there was no control group. Pulmonary rehabilitation involved educational and physical training sessions and was carried out daily for 4 -6 weeks. Exercise intensity was personalized based on individual tolerance, physiologic parameters, or physiotherapist judgment. RESULTS: Upon completion of pulmonary rehabilitation, a significant improvement in 6-min walk distance was observed (P ‫؍‬ .04). The dyspnea score at the end of the 6MWT improved as well, although the improvement did not reach statistical significance (P ‫؍‬ .06). These changes were not confirmed at a 12-month follow-up visit. No significant effects of pulmonary rehabilitation on arterial blood gases were observed. CONCLUSIONS: A combined intervention including a tailored pulmonary rehabilitation program together with LTOT and NIV seems to be of short-term benefit in subjects with kyphoscoliosis and severe respiratory impairment.

show abstract

“…There is an inevitable natural decline in pulmonary function with aging, which may be more pronounced in patients with untreated spinal deformity [1][2][3] . Some adults with spinal deformity present with substantially reduced pulmonary function, and an important unanswered question is whether corrective/fusion surgery in patients with preoperative pulmonary impairment can improve pulmonary function 4 , or, more importantly, if surgical treatment results in a substantial worsening in pulmonary status 5 .…”

mentioning

confidence: 99%

“…Zhang et al also noted that the incidence of postoperative pulmonary complications was eighteen times greater for adult patients with spinal deformity who underwent transthoracic procedures compared with posterior-only approaches 43 . Despite this high rate of early postoperative pulmonary complications, there have been limited reports to date evaluating long-term pulmonary function in this patient population 1,4,5 . Pehrsson et al evaluated twenty-four patients with surgically untreated severe idiopathic scoliosis, who ranged in age between fifteen and sixty-seven years, and found over a twentyyear period that pulmonary function decreased by the same magnitude as predicted decline due to age 1 .…”

mentioning

confidence: 99%

Pulmonary Function Following Adult Spinal Deformity Surgery: Minimum Two-Year Follow-Up

Lehman

Kang²,

Lenke

et al. 2013

The Spine Journal

View full text Add to dashboard Cite

show abstract

Lung function in adult idiopathic scoliosis: a 20 year follow up.

Cited by 143 publications

References 16 publications

Relationship between pulmonary function and degree of spinal deformity, location of apical vertebrae and age among adolescent idiopathic scoliosis patients

Relationship between pulmonary function and degree of spinal deformity, location of apical vertebrae and age among adolescent idiopathic scoliosis patients

Pulmonary Rehabilitation Improves Exercise Capacity in Subjects with Kyphoscoliosis and Severe Respiratory Impairment

Pulmonary Function Following Adult Spinal Deformity Surgery: Minimum Two-Year Follow-Up

Contact Info

Product

Resources

About