Lung cell reactions in guinea pigs after inhalation of asbestos (amosite)

Sjöstrand, Margareta; Rylander, Ragnar; Bergström, R

doi:10.1016/0300-483x(89)90030-9

Cited by 11 publications

(4 citation statements)

References 18 publications

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“…Cathepsin D activity was significantly changed after amosite inhalation. These results are in good accordance with the work of Sjörstrand et al (11).…”

Section: Discussionsupporting

confidence: 94%

Combined Effect of Selected Mineral Fibres and Tobacco Smoke on Respiratory Tract in Rats

Hurbánková¹,

Hraškov²,

Beňo³

et al. 2014

Cent Eur J Public Health

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The rats were inhaling amosite and wollastonite fibres at two concentrations (30 and 60 mg/m3) one hour every second day and cigarette smoke of 3 cigarettes per day (with the exception of Saturdays and Sundays). They were sacrificed after 6 month of exposure. Bronchoalveolar lavage (BAL) was performed and selected inflammatory and cytotoxic parameters were examined. Amosite: inflammatory parameters were the most changed after 60 mg/m3 in both groups with or without smoking; the cytotoxic parameters were strongly influenced by smoking. Wollastonite (asbestos substitute) inhalation confirmed lower inflammatory and cytotoxic effects on all examined animal groups in comparison with amosite.

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“…Cathepsin D activity was significantly changed after amosite inhalation. These results are in good accordance with the work of Sjörstrand et al (11).…”

Section: Discussionsupporting

confidence: 94%

Combined Effect of Selected Mineral Fibres and Tobacco Smoke on Respiratory Tract in Rats

Hurbánková¹,

Hraškov²,

Beňo³

et al. 2014

Cent Eur J Public Health

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“…Cathepsin D activity was significantly changed after amosite inhalation. These results are in good accordance with study of Sjörstrand et al (1989). Wollastonite inhalation confirmed the lower cytotoxicity in comparison with asbestos.…”

Section: Combined Effect Of Mineral Fibers and Tobacco Smoke On Respisupporting

confidence: 91%

Immune System and Environmental Xenobiotics - The Effect of Selected Mineral Fibers and Particles on the Immune Response

Kuricová¹,

Tulinská²,

Líšková³

et al. 2012

Recent Advances in Immunology to Target Cancer, Inflammation and Infections

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“…Shorter fibers can be phagocytosed by alveolar macrophages and removed by ciliated epithelium in the proximal airways [29]. Asbestos accumulation in guinea pig macrophages could still be seen 2 years after a 6-week exposure to amosite [30]. Similarly, our results indicated that macrophages were accumulated and co-localized with inhaled fibers in the hilar lymph nodes suggesting that macrophage migration does act as a mechanism to transport small inhaled fibers from the lung parenchyma to the hilar lymph nodes.…”

Section: Discussionsupporting

confidence: 65%

Elemental and immunohistochemical analysis of the lungs and hilar lymph node in a patient with asbestos exposure, a pilot study

Koga

Satoh

Kaira

et al. 2016

Environ Health Prev Med

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Lung cell reactions in guinea pigs after inhalation of asbestos (amosite)

Cited by 11 publications

References 18 publications

Combined Effect of Selected Mineral Fibres and Tobacco Smoke on Respiratory Tract in Rats

Combined Effect of Selected Mineral Fibres and Tobacco Smoke on Respiratory Tract in Rats

Immune System and Environmental Xenobiotics - The Effect of Selected Mineral Fibers and Particles on the Immune Response

Elemental and immunohistochemical analysis of the lungs and hilar lymph node in a patient with asbestos exposure, a pilot study

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