Lung carcinoma in patients age younger than 30 years

Mizushima, Yutaka; Yokoyama, Akira; Ito, Masami; Manabe, Hideo; Hirai, Takashi; Matsuda, Hiroyuki; Anzai, Yoshiyuki; Sato, Hideo; Kusajima, Yoshinori; Yamashita, Ryohei; Kobayashi, Kouichirou; Sugiyama, Shigeki; Kobayashi, Masashi

doi:10.1002/(sici)1097-0142(19990415)85:8<1730::aid-cncr12>3.0.co;2-g

Cited by 18 publications

(4 citation statements)

References 16 publications

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“…Their prognosis was similar to that of older patients [12,13]. Analyzing 26 patients below 30 years, Mizushima et al [14] found a more favorable prognosis in the young patients, however, there was a low incidence of squamous cell carcinoma and a predominance of stage I.…”

Section: Discussionmentioning

confidence: 72%

Non-small cell lung carcinoma in an adolescent manifested by acute paraplegia due to spinal metastases: a case report

2011

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IntroductionBronchial carcinomas in childhood and adolescence are extremely rare; only individual cases have been reported previously.Case presentationWe report on a 16-year-old Caucasian German boy with non-small cell lung carcinoma (squamous cell non-small cell lung carcinoma) stage IV, T4N2M1, without epidermal growth factor receptor overexpression and/or mutation or k-ras mutation. He presented with paraplegia due to spinal metastases of the bronchial carcinoma. No familial predisposition or toxin exposure was identified. Treatment following adult protocols consisted of surgical intervention for spinal metastases, first-line cisplatinum and gemcitabine, irradiation and second-line docetaxel. After a transient response our patient experienced disease progression and died about 10 months later.ConclusionResponse and survival in our 16-year-old patient were similar to adult patients with stage IV non-small cell lung carcinoma.

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Section: Discussionmentioning

confidence: 72%

Non-small cell lung carcinoma in an adolescent manifested by acute paraplegia due to spinal metastases: a case report

2011

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“…Survival in this group of patients remains highly variable. Mizushima et al found no difference in survival between lung Adenocarcinoma patients less than or more than 30 years of age [11].…”

Section: Discussionmentioning

confidence: 98%

“…Most of the young patients are male (41.7%) and smokers (33.37%) [10]. In reference to NSCLC occurring in young people, a higher incidence of Adenocarcinoma is seen in female patients, and in the majority of these cases there is no history of tobacco use [11].…”

Section: Discussionmentioning

confidence: 99%

Malignant Pleural Mesothelioma and Lung Cancer in a Very Young Age

2019

JCRC

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The presence of cancer of the lungs is rare in adolescent patients, particularly in those under 20 years of age. A cancer that begins in the lungs is most often found in older patients with a history of tobacco use. In literature cancer in younger patients mostly meditational origins. Hence, we found two cases of lung cancer in a 15 and 17 years old male with different clinical presentation and history. In this paper, we hope to illustrate the unique challenges in diagnosing and treating young patients with lung cancer. The third case is 29 years old young man with malignant pleural mesothelioma which is a rare, invasive and often fatal neoplasm that develops in the thin layer of tissue surrounding the lungs known as the pleura. Although rare, mesotheliomas do occur in the young; their characteristics are distinct from those of older patients.

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“…Other studies, however, tend to show that women have higher morbidity rates than men for chronic conditions such as cancer. Mizushima et al . (1999) observed that there was a higher incidence of lung carcinoma among female patients who were less than 30 years of age.…”

Section: Introductionmentioning

confidence: 99%