Lung cancer with superior vena cava syndrome diagnosed by intravascular biopsy using EBUS-TBNA

Abstract

Since superior vena cava syndrome (SVCS) is a critical condition, immediate diagnostic approach and therapy are imperative to avoid potentially life-threatening complications. Here, we report a case of lung cancer with SVCS, which was diagnosed through intravascular tumor biopsy using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). EBUS-TBNA enabled us to obtain tissue sufficient for diagnosis, without significant complications. Prompt diagnosis was followed by appropriate anticancer treatment and improvement in the symptoms. For patients suspected of SVCS and requiring prompt pathologic diagnosis, we can consider EBUS-TBNA to diagnose intravascular or mediastinal tumors and provide an accurate diagnosis.

Left Atrial Tumor Thrombus in a Patient With Squamous Cell Carcinoma of Lung

“…In patients with RCC, tumor thrombus extends along the inferior vena cava as a result of underlying RCC or along the portal vein from hepatocellular carcinoma (HCC) [2]. Lung cancer can invade SVC causing SVC syndrome [3]. However, it is very rare for patients with non-small lung cancer to have extensive SVC thrombosis with erosion into LA causing almost complete obliteration of left atrial cavity [4].…”