Lung Cancer (Squamous Cell Carcinoma) in Adolescence

Abstract

Primary lung cancer is rare in childhood. An asymptomatic 15-year-old boy was found to have a solitary circular shadow by a mass chest photofluorographic survey. The clinical course strongly suggested malignant tumor. Lobectomy three months after the detection of the shadow showed squamous cell carcinoma. At present, 3\m=1/2\years after surgery, the patient is healthy and attending school. Cases of primary lung cancer in childhood are reviewed.While the frequency of primary carcinoma of the lung has re¬ cently increased remarkably in adults, it is rare in childhood. Here we report a case of lung cancer (squamous cell carcinoma) found in a 15-year-old boy by a mass chest photofluorographic survey.The patient, a boy 15 years and 7 months of age, was a pupil of the third grade in middle school. No history of familial dis¬ ease, including malignancy, was obtained. He had enjoyed good health. He had never smoked, and his environment had not been unusual.From a mass survey for the detection of pulmonary tuberculosis on Jan 21, 1969, a photofluorogram of the chest showed ab¬ normal findings. Six days after the survey photofluoro¬ gram, at which time he had no complaints, a roentgenogram showed a solitary circu¬ lar shadow of homogeneous density 2.5 cm

Primary bronchogenic squamous cell carcinoma in children: Report of a case and review of the literature

“…There were no clearly identifiable risk factors. Age at onset was 1 year [6],2 years [8], 5 years [51, 10 years [7], 12 years (our case), and 15 years (8). While five of the six patients were boys, this male predominance is not significant owing to the small number of cases.…”

Solitary pulmonary nodule in an early adolescent

“…In addition, malignancy was only seen in the setting of pulmonary nodules ≥7 mm in diameter in children with a history of malignancy,6 suggesting that further imaging workup is warranted only for patients with pulmonary nodules ≥7 mm and a history of malignancy. However, there are also multiple case reports describing primary lung malignancies presenting as incidental pulmonary nodules in paediatric patients 7–9. As such, a recent review by a panel of paediatric radiologists acknowledged that while it is extremely rare for paediatric lung cancer to arise from an incidental pulmonary nodule, there is insufficient evidence to categorically disregard the possibility of lung cancer arising from an incidental pulmonary nodule 5.…”

Primary squamous cell carcinoma of lung in a 13-year-old boy: a case report

“…Cayler et al [ 1 ] in 1951 reported 16 cases of primary carcinoma of the lung in children less than 15 years of age Primary bronchogenic squamous cell carcinoma is extremely rare in childhood and adolescence. Eight histologically confirmed cases reported in the English literature [ 2 - 9 ] are summarized along with the present case [Table 1].…”

“…In 1974, Niitu et al [ 2 ] reported one case of squamous cell carcinoma in a boy and reviewed the world literature and found 39 cases of primary lung cancer in children less than 16 years of age. These cases included two cases of bronchogenic squamous cell carcinoma [ 6 , 8 ].…”