Lung cancer in Teesside (UK) and Varese (Italy): a comparison of management and survival

Imperatori, Andrea; Harrison, Richard; Leitch, David N.; Rovera, Francesca; Lepore, Giovanni; Dionigi, Gianlorenzo; Sutton, P.H.; Dominioni, Lorenzo

doi:10.1136/thx.2005.040477

Cited by 75 publications

(78 citation statements)

References 25 publications

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“…2 Subsequent studies have described differences in management and survival between the UK and other comparable European countries. 3,4 It has always been unclear to what extent such variation could be explained by casemix variables (ie patients diagnosed later with more advanced disease or multiple co-morbidities) and to what extent they are the result of differences in standards of specialist care, highlighting the need to establish a high quality national lung cancer audit (NLCA), with the aim of recording information about activity, process and outcomes in lung cancer and, using casemix adjustment, begin to explain the wide variations in outcome. Although the UK cancer registries have collected data on lung cancer since the 1970s they have limited information on a number of important factors, including treatment and the key casemix variables, particularly stage.…”

Section: Introductionmentioning

confidence: 99%

Exploring variations in lung cancer care across the UK–the ‘story so far' for the National Lung Cancer Audit

et al. 2012

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-The National Lung Cancer Audit was developed to improve the quality and outcomes of services for patients with lung cancer, knowing that outcomes vary widely across the UK and are poor compared to other western countries. After five years the audit is capturing approximately 100% of the expected number of incident cases across hospitals in England, Wales, Scotland, Northern Ireland and Jersey. Measures of process and outcome have improved over the audit period, such as the histological confirmation rate (64-76%), the proportion of patients discussed in a multidisciplinary team meeting (78-94%), and the proportion of patients having anti-cancer treatment (43-59%), surgical resection (9-14%) and small cell lung cancer chemotherapy (58-66%). These national averages hide wide variations between hospitals providing lung cancer care which cannot be accounted for by differences in casemix. This paper describes the evolution of the audit, and describes the ways in which it may have improved clinical practice.

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Section: Introductionmentioning

confidence: 99%

Exploring variations in lung cancer care across the UK–the ‘story so far' for the National Lung Cancer Audit

et al. 2012

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“…There is a wide variation between the different populations in the proportion of those diagnosed incidentally. Looking at countries like ours, it can vary between the 7% reported in Swedish or Italian studies, 20,22 to up to 21% in an English population. 22 However, the fact that the diagnosis of LC was incidental does not imply that the patient was asymptomatic, as shown in our study.…”

Section: 15mentioning

confidence: 74%

“…Looking at countries like ours, it can vary between the 7% reported in Swedish or Italian studies, 20,22 to up to 21% in an English population. 22 However, the fact that the diagnosis of LC was incidental does not imply that the patient was asymptomatic, as shown in our study. In a Swedish study, that clearly differentiated between the symptoms of the patient and the consulting reason that led to the cancer diagnosis, 7% incidental diagnoses were reported, although almost 97% of the patients had symptoms associated with LC at the time of the diagnosis.…”

Section: 15mentioning

confidence: 74%

Symptoms and Reason for a Medical Visit in Lung Cancer Patients

González‐Barcala¹,

Falagan

Prim³

et al. 2014

Acta Med Port

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Background:Patients with lung cancer usually present with symptoms at the time of diagnosis, but it is common that neither the doctor nor the patient initially associate them with the possibility of a malignant tumour. Objectives: The aim of our study is to analyse the symptoms of patients with lung cancer and the relationship with the personal characteristics or the oncological disease. Material and Methods:A retrospective study was conducted on all patients diagnosed with lung cancer in the Pontevedra Health Area over a period of three years. The symptoms presented by the patient, the reason for the consultation and the agreement between both or any factors associated with either of the two are analysed.Results: A total of 358 patients, with a mean age of 68.7 years, and of whom 87% males, were included in the study. The most common initial symptoms were, constitutional in 30.4% of the cases, cough in 20.9% of cases, and in third place was chest pain, which was referred to by 12% of the patients. The most frequent reason for the consultation was dyspnea in 22.1% of patients, an incidental finding in 15.4%, and haemoptysis in 12.8%. There was a moderate association (correlation coefficient = 0.495) between the initial symptoms and the consulting symptom. Conclusions: A high percentage of patients with lung cancer had symptoms associated with the tumour at the time of diagnosis, even in early stage disease.

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“…Data from the UK National Lung Cancer Audit in 2009 found that the overall unadjusted proportion of patients who underwent surgical resection was approximately 11%, with regional variations ranging from less than 5% to greater than 25%. [46] Other countries in Europe had much higher rates of resection, such as Italy (24%), [47] the Netherlands (20%) [48] and Sweden (17.5%). [49] The group in the UK suggested that lower resection rates were due to diminished access to specialist thoracic surgeons.…”

Section: Discussionmentioning

confidence: 99%

A 2-year retrospective review of the effect of cigarette smoking status on the histological cell types of lung carcinoma in the Western Cape

Pellizzon¹,

Koegelenberg²,

Irusen³

2015

S Afr Res J

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Background. Cigarette smoking is variably associated with the various histological cell types of lung cancer. The primary aim of this study was to analyse various strengths of association between the common histological cell types of lung cancer and smoking in a Western Cape population. The secondary aim examined whether an association exists between scar carcinoma and smoking. Methods. We retrospectively analysed the records from 386 patients over a 2-year period. Both smokers and non-smokers were subdivided and analysed as two groups, which included those with non-small cell and small cell lung cancer. Smokers and non-smokers were also analysed separately according to the presence or absence of lung scarring. Results. In total, 94.3% of all patients with lung cancer were current or past smokers. There was a disproportionately higher number of patients with adenocarcinoma who were non-smokers compared with all the other cell types (p=0.01), whereas patients with squamous cell carcinoma were more likely to be smokers (p=0.05). Although the vast majority of patients with and without lung scars were found to be smokers (96.4% v. 93.7% respectively), there was no statistically significant difference found between these two groups (p=0.43). Conclusion. In a Western Cape population, patients with adenocarcinoma were more likely to be non-smokers, while those with squamous cell carcinoma were relatively more likely to be smokers. No clear association between scar carcinoma and smoking status was found.

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Lung cancer in Teesside (UK) and Varese (Italy): a comparison of management and survival

Cited by 75 publications

References 25 publications

Exploring variations in lung cancer care across the UK–the ‘story so far' for the National Lung Cancer Audit

Exploring variations in lung cancer care across the UK–the ‘story so far' for the National Lung Cancer Audit

Symptoms and Reason for a Medical Visit in Lung Cancer Patients

A 2-year retrospective review of the effect of cigarette smoking status on the histological cell types of lung carcinoma in the Western Cape

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