Lung Cancer in Patients with Human Immunodeficiency Virus Infection Compared with Historic Control Subjects

Sridhar, Kasi S.; Flores, Maria Regina C.; Raub, William; Saldana, Mario J.

doi:10.1378/chest.102.6.1704

Cited by 92 publications

(76 citation statements)

References 13 publications

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“…Secondly, it was speculated that patients with HIV infection tolerated chemotherapy less well resulting in dose reductions that entailed lower response rates (Wilson et al, 1992;Hentrich et al, 1996). The third possible reason for the decreased survival was due to more aggressive tumours in this group or intrinsic chemotherapy resistance in patients with HIV (Tessler and Catanese, 1987;Sridhar et al, 1992;Vyzula and Remick, 1996). Since the introduction of HAART, HIV-related mortality has decreases and the outcome of patients with Kaposi's sarcoma and lymphomas have improved (Tam et al, 2002).…”

Section: Discussionmentioning

confidence: 99%

Outcome of patients with HIV-related germ cell tumours: a case–control study

et al. 2004

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Testicular germ cell tumour (GCT) is not an AIDS-defining illness despite an increased incidence in men with HIV infection. We performed a matched case-control study comparing outcomes in HIV-positive men and the general population with GCT, using three age and stage matched controls for each case. There was no difference in the 5-year GCT-free survival between cases and controls. However, overall survival was significantly decreased in the cases (log rank P ¼ 0.03). HIV was responsible for 70% of this mortality. The relapse-free survival for stage I patients treated with orchidectomy and surveillance was not affected by HIV status (log rank P ¼ 0.68). There was no difference in disease free survival in patients with metastatic disease (log rank P ¼ 0.78). The overall survival has not improved since the introduction of highly active antiretroviral therapy (log rank P ¼ 0.4). Thus, HIV-related GCT is not more aggressive than GCT in the general population.

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Section: Discussionmentioning

confidence: 99%

Outcome of patients with HIV-related germ cell tumours: a case–control study

et al. 2004

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“…Cervical lavage specimens were tested for human papillomavirus (HPV) by PCR in a single laboratory. HPV type was identified by hybridization with a generic probe designed to recognize most HPV types and with typespecific probes for the HPV types, based on their associations with cervical cancer: 16 20 HPV types of multiple risk categories were categorized according to the highest risk HPV type in the specimen.…”

Section: Methodsmentioning

confidence: 99%

Cancer incidence in women with or at risk for HIV

et al. 2001

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“…21 HIV+ smokers also have lower CD4 cell counts, higher HIV viral loads, and lower self-reported quality of life than HIV+ nonsmokers. [19][20][21][22] Smokers are also more likely to progress to an AIDS diagnosis, 23 have poorer response to ART, 12 and are more likely to be nonadherent to ART. 24 Importantly, longer duration of abstinence from smoking substantially reduces HIV symptom burden.…”

Section: Smoking-related Morbidity and Mortality Among Plwhamentioning

confidence: 96%

Smoking Cessation for People Living With HIV/AIDS: A Literature Review and Synthesis

Ledgerwood

Yskes

2016

NICTOB

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Introduction: People living with HIV/AIDS (PLWHA) are more likely to smoke cigarettes than are individuals in the general population. The health implications of tobacco use are substantially more dire among PLWHA than among otherwise healthy smokers, including higher rates of various cancers, cardiovascular disease, inflammation, and lung infections. Efficacious behavioral and medication treatments for treating nicotine dependence have rarely been investigated in PLWHA. Methods: We present a review of studies examining the efficacy of smoking cessation interventions. Results and Conclusions:The literature reveals some limited evidence for the efficacy of behavioral interventions. However, the research literature on these interventions is sparse and the efficacy findings are mixed. Studies exploring the use of mobile technologies for reducing treatment barriers are becoming more prevalent. Few published trials have directly examined the efficacy of pharmacological smoking cessation interventions among PLWHA. Specific gaps in the treatment literature are discussed in detail, and a strategy is presented for developing a greater understanding of factors that contribute to the efficacy of smoking cessation among PLWHA. Implications: This paper provides the most comprehensive review to date on smoking cessation intervention research conducted with PLWHA. It also discusses specific gaps in the literature that should be a priority for future research.

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Lung Cancer in Patients with Human Immunodeficiency Virus Infection Compared with Historic Control Subjects

Cited by 92 publications

References 13 publications

Outcome of patients with HIV-related germ cell tumours: a case–control study

Outcome of patients with HIV-related germ cell tumours: a case–control study

Cancer incidence in women with or at risk for HIV

Smoking Cessation for People Living With HIV/AIDS: A Literature Review and Synthesis

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