Lung biopsy assessment with dynamic cell optical imaging (Conference Presentation)

Motion artifact removal and signal enhancement to achieve in vivo dynamic full field OCT

“…In the laboratory, we succeeded in stabilizing the setup by mounting it on a sturdy optical bench, and carried out ex vivo experiments without motion artifacts. For real life applications however, D-FFOCT devices are currently being used by clinicians in hospitals for imaging biopsied tissues [19] and by anatomo-pathologists in busy environments with vibrations arising from vibrational modes of the building, from people walking around the device and from air conditioning. Mechanical vibrations can lead to sample arm motion or oscillations, creating strong signal fluctuations, especially from highly reflective structures such as collagen fibers.…”