Lumpy Skin Disease Virus

Weiss, Karen E.

doi:10.1007/978-3-662-39771-8_3

Cited by 175 publications

(214 citation statements)

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“…This hypothesis is supported by the observation that LSD outbreaks are correlated with warm and wet seasons [5]. Previous studies have demonstrated the transmission of sheeppox and goatpox virus by Stomoxys calcitrans (L.) stable flies [6] and LSDV by Aedes aegypti (L.) mosquitoes [7], respectively.…”

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confidence: 73%

“…LSD causes severe production losses in infected herds, largely through sharp drops in milk yield and weight gain, infertility in both male and female stock and abortions. In addition, the decreased value of hides due to permanent scarring caused by the skin lesions contributes to the economic impact [2][3][4][5]. While reports on the overall socioeconomic impact of LSD in developing countries are limited, losses due to decreased milk production alone were estimated to be in the range of 40-65% in an intensive milk-producing unit of 3200 cattle during a LSD outbreak that occurred in the Sultanate of Oman in 2010 [4].…”

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confidence: 99%

“…Body temperature was recorded daily and blood samples (EDTA and serum) were collected on 0, 3,4,5,6,7,10,11,12,13,14,15,16,17,18,19,20,21,24 and 26 dpi after the transfer of partially fed ticks. Serum samples were tested for neutralizing antibodies using a constant-virus/varying-serum neutralization test [8].…”

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confidence: 99%

“…The recipient animal began to seroconvert 20 days after the attachment of the infected R. appendiculatus ticks and remained seropositive until the last serum sample was collected at 26 dpi by R. appendiculatus ticks. Antibody titres in the recipient animal varied from 1:5 to 1:10, which is typical for animals suffering from mild clinical LSD [5].…”

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confidence: 99%

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Mechanical transmission of lumpy skin disease virus by Rhipicephalus appendiculatus male ticks

et al. 2012

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SUMMARYLumpy skin disease (LSD) is an economically important, acute or sub-acute, viral disease of cattle that occurs across Africa and in the Middle East. The aim of this study was to investigate if lumpy skin disease virus (LSDV) can be transmitted mechanically by African brown ear ticks (Rhipicephalus appendiculatus Neum.). Laboratory-bred R. appendiculatus males were fed on experimentally infected viraemic 'donor ' cattle. Partially fed male ticks were then transferred to feed on an uninfected ' recipient ' cow. The recipient animal became viraemic, showed mild clinical signs of LSD and seroconverted. Additionally, R. appendiculatus males were found to transmit LSDV through feeding on skin lacking visible lesions, demonstrating that viraemic animals without lesions at the feeding site of ticks may be a source of infection. This is the first time that transmission of poxviruses by a tick species has been demonstrated and the importance of this mode of transmission in the spread of LSDV in endemic settings is discussed.

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confidence: 73%

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confidence: 99%

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confidence: 99%

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confidence: 99%

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Mechanical transmission of lumpy skin disease virus by Rhipicephalus appendiculatus male ticks

et al. 2012

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“…In experimentally infected animals, live LSDV has also been isolated from healthy looking skin (Weiss, 1968) and for up to 39 dpi in skin lesions that are known to contain higher titres of virus than the blood (Babiuk et al, 2008b). In this study, we were not able to determine if each life cycle stage of the ticks became infected separately or whether the virus survived the moulting process from one stage to the next.…”

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confidence: 94%