Lumbar Myelography Today: Experience With Metrizamide, a Water‐soluble. Non‐ionic Contrast Medium

The series consisted of 200 patients on whom lumbar myelography was performed for sciatica. After myelography, a disc operation was carried out on 95 patients. The episode of sciatica was the first for 90 patients. Objective neurologic signs were present in 185 patients, while 15 had only subjective symptoms. Definite or possible disc herniation was revealed by myelography in 66%. Most positive findings were located at the L4-L5 interspace. The clinical diagnostic accuracy rate was assessed from the patients' histories. As confirmed by operation, the accuracy of the clinical diagnostics was 52%, and the accuracy rate of myelography was 90%. The rate of false positive findings in myelography was 4%, that of false negative findings 6%. When the clinical or myelographic diagnosis was definitive, a disc herniation or protrusion was always found at operation. Almost one fourth of the clinically diagnosed definite herniations were not treated surgically because myelography proved negative. One fifth of those patients in whom myelography revealed an unequivocal disc herniation were not operated on because these patients had clinically improved before being admitted to myelography. The results of this study justify the following conclusions: the clinical level diagnostics of a disc herniation is rather unreliable, and myelography is therefore always indicated before operation; myelography should only be performed in those cases in which there is a clear clinical indication for surgery; myelography ought to be performed within 1 week; an unequivocal positive finding in myelography predicts a good operative result.

show abstract

Myelographic versus clinical diagnostics in lumbar disc disease

Aejmelaeus

Hiltunen

Härkönen

et al. 1984

Arch. Orth. Traum. Surg.

View full text Add to dashboard Cite

show abstract

Acute chemical meningitis after metrizamide-lumbar myelography

Worthington¹,

Callander²,

Flynn³

et al. 1983

Surgical Neurology

View full text Add to dashboard Cite

Myelography with Metrizamide—An Analysis of the Complications Encountered in Cervical, Thoracic and Lumbar Myelography

McCormick

ApSimon

Chakera

1981

Australian and New Zealand Journal of Medicine

View full text Add to dashboard Cite

Myelography with metrizamide-an analysis of the complications encountered in cervical, thoracic and lumbar myelography. C. C. McCormick, H. T. Apsimon and T. M. H. Chakera. /lust. N.Z. J. M e d . , 1981, 11, pp. 645-650.Detailed analysis of complications in 363 patients undergoing myelography with metrizamide is presented. Patients have been separated into three groups: those who had lumbar myelograms via lumbar puncture; patients who had cervical myelograms via lumbar route and patients who had cervical myelograms via cervical puncture (lateral ClIC2. approach).Analysis has revealed that the incidence of minor complications like headaches, nausea, and vomiting is higher than that associated with myodil myelography. Nevertheless, it is concluded that because of lack of long term disability of arachnoiditis, and because of greater diagnostic accuracy, mefrizamide represents the best contrast medium for myelography currently available.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Lumbar Myelography Today: Experience With Metrizamide, a Water‐soluble. Non‐ionic Contrast Medium

Cited by 5 publications

References 15 publications

Myelographic versus clinical diagnostics in lumbar disc disease

Myelographic versus clinical diagnostics in lumbar disc disease

Acute chemical meningitis after metrizamide-lumbar myelography

Myelography with Metrizamide—An Analysis of the Complications Encountered in Cervical, Thoracic and Lumbar Myelography

Contact Info

Product

Resources

About