Ludwig's angina in pregnancy and puerperium: Case series in an academic hospital, Sokoto, Northwest Nigeria

Braimah, RamatOyebunmi; Ibikunle, AdebayoAremu; Taiwo, AbdurrazaqOlanrewaju; Tunau, K

doi:10.4103/sjhs.sjhs_17_17

Cited by 1 publication

(2 citation statements)

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“…[45] It is a condition well known to be associated with high morbidity and mortality. [7] The relatively high frequency of the condition and associated mortality could, in part, be attributed to low socioeconomic status. [515] This study showed that there was no statistically significant difference in swelling reduction, trismus, and length of hospital stay among the patients treated with the two drugs, thus making the cheaper and more readily available benzylpenicillin a suitable empirical alternative, where Augmentin cannot be afforded or unavailable to reduce mortality associated with the condition.…”

Section: Discussionmentioning

confidence: 99%

“…[4] Although Ludwig's angina often results as a complication of severe odontogenic infection, several other etiological and risk factors have also been implicated. These include diabetes mellitus,[45] HIV infection,[4] pregnancy,[6] puerperium,[7] alcoholism,[3] chronic malnutrition,[8] and low socioeconomic status. [9] The peculiarity of Ludwig's angina among odontogenic infections is its propensity for rapid spread, capable of leading to airway obstruction, carotid arterial rupture or sheath abscess, thrombophlebitis of the internal jugular vein, mediastinitis, empyema, necrotizing fasciitis, pericardial effusion, osteomyelitis, and septicemia.…”

Section: Introductionmentioning

confidence: 99%

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A comparative study of the efficacy of intravenous benzylpenicillin and intravenous augmentin in the empirical management of Ludwig's angina

et al. 2019

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Background: Ludwig's angina is a potentially life-threatening condition characterized by bilateral cellulitis of the submandibular, submental, and sublingual spaces. Intravenous (I.V) penicillin G or amoxicillin-clavulanate (Augmentin) has been recommended for use as empirical management before obtaining culture and sensitivity results. Aim: The aim of this study was to compare the therapeutic efficacies and clinical outcomes of I.V benzylpenicillin with I.V Augmentin in the empirical management of Ludwig's angina. Methods: This was a prospective randomized clinical study carried out to measure the rate of swelling reduction (using the lobar rate, Adam's rate, and interincisal distance) and other clinical parameters among the two drug groups (I.V penicillin G and Augmentin). Descriptive summaries of variables were generated, and Student's t -test was used to compare the mean outcomes of the two groups. Results: A total of 26 individuals participated in the study, consisting of 46% (12) males and 54% (14) females. The participants ranged from 13 to 61 years with mean and median of 34.4 (±12.7) and 35 years, respectively. Only 8% of the cases of Ludwig's angina were not attributable to odontogenic factors, compared to 92% resulting from odontogenic causes. There was no significant difference in the efficacy of the two antibiotics used in this study. Conclusion: The efficacies and the clinical outcomes of the two antibiotics were similar. Benzylpenicillin is probably a suitable empirical alternative where Augmentin cannot be afforded, to reduce the mortality associated with the condition.

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Section: Discussionmentioning

confidence: 99%