Ludwig angina and sudden death

Tu, Abbie; Gilbert, John D.; Byard, Roger W.

doi:10.1007/s12024-020-00350-0

Cited by 6 publications

(7 citation statements)

References 15 publications

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“…Intubation should be performed for patients with airway obstruction for whom a CT scan has not been performed, as this can cause a critical delay that can lead to death. 12 In Ludwig's angina, microbial infection occurs, resulting in an inflammatory reaction in an attempt to fight and destroy pathogens. This inflammatory reaction can be recognized from clinical examination by the presence of hyper or hypothermia, tachycardia, tachypnea, hypotension, and signs of inflammation locally at the site of infection, such as skin redness, warmth, pain, and edema.…”

Section: Discussionmentioning

confidence: 99%

The use of Neutrophil – Lymphocyte Ratio (NLR) as a potential biomarker to predict the prognosis of Ludwig's angina patients

2022

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Background: Ludwig's angina is an infection of the submandibular cavity in the form of cellulitis that is rapidly progressive and potentially life-threatening. Neutrophils and lymphocytes play an important role in this infection process. Neutrophil-lymphocyte Ratio (NLR) is a simple biomarker to evaluate systemic inflammation. We aimed to determine the association between NLR and various prognostic parameters in patients with Ludwig's Angina. Methods: A retrospective cohort study was conducted using medical records of Ludwig's Angina patients treated at Dr. Soetomo General Hospital, Surabaya, Indonesia, between January 2018 – December 2021. The NLR cut-off value was calculated using the receiver operating characteristics (ROC) curve. The association between NLR with severity, length of stay (LoS), and mortality were analyzed using SPSS version 23 for Windows. Results: We recruited a total of 96 patients. NLR values are divided categorically into low NLR and high NLR using a cut-off value of 16.86. There were 49 patients (51%) with low NLR and 47 (49%) with high NLR. There was a significant relationship between NLR with severity, LoS, and mortality in Ludwig’s angina patients (p=0.032, p=0.002, and p=0.026, respectively). According to a survival study, the high NLR group's survival rate was significantly lower than the low NLR group's (p=0.009). Conclusion: There was a significant relationship between NLR severity grading, survival, and the length of stay in patients with Ludwig's Angina.

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Section: Discussionmentioning

confidence: 99%

The use of Neutrophil – Lymphocyte Ratio (NLR) as a potential biomarker to predict the prognosis of Ludwig's angina patients

2022

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“…Its origin is odontogenic in 90% of the cases,10 and it may result in mortality. Although Ludwig’s angina is rarely seen in the ED, mortality has been reported 7 11 12. Endotracheal intubation must be performed before the patient has stridor or cyanosis.…”

Section: Discussionmentioning

confidence: 99%

“…Mortality due to upper airway obstruction has been reported in Ludwig’s angina with an odontogenic origin 11 12. Narrowing of the oral cavity due to dental abscess may necessitate supraglottic airway management, and oedema of the floor of the mouth may cause difficult endotracheal intubation 13.…”

Section: Discussionmentioning

confidence: 99%

Complications of dental infections due to diagnostic delay during COVID-19 pandemic

Altıntaş

2022

BMJ Case Rep

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We present three cases who presented to the emergency department with severe complications of dental infections: Ludwig’s angina, necrotising fasciitis and peritonsillar abscess. All of our cases presented at the beginning of COVID-19 pandemic, with complications of dental infections. They delayed their dental treatment due to the pandemic. The airway management was difficult in our cases. Their mortality risk increased due to complications. We aimed to draw attention to complicated odontogenic infections which are rarely seen in emergency department in the past, however started to show up increasingly particularly at the beginning of the COVID-19 pandemic.

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“…The infection spreads from the apical area below the mylohyoid muscle into the submandibular space and elevates the floor of the mouth. It also spreads to the pharyngomaxillary and retropharyngeal spaces, narrowing the airway 25,31–34 …”

Section: Surgical/clinical Relevancementioning

confidence: 99%

“…It also spreads to the pharyngomaxillary and retropharyngeal spaces, narrowing the airway. 25,[31][32][33][34]…”

Section: Surgical/clinical Relevance Inflammatory Diseasesmentioning

confidence: 99%

Mylohyoid Muscle: Current Understanding for Clinical Management Part II: Clinical Anatomy, Radiology, and Surgical/Clinical Relevance

Obata,

Kitagawa,

Ono

et al. 2023

Journal of Craniofacial Surgery

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Ludwig angina and sudden death

Cited by 6 publications

References 15 publications

The use of Neutrophil – Lymphocyte Ratio (NLR) as a potential biomarker to predict the prognosis of Ludwig's angina patients

The use of Neutrophil – Lymphocyte Ratio (NLR) as a potential biomarker to predict the prognosis of Ludwig's angina patients

Complications of dental infections due to diagnostic delay during COVID-19 pandemic

Mylohyoid Muscle: Current Understanding for Clinical Management Part II: Clinical Anatomy, Radiology, and Surgical/Clinical Relevance

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