Lubricant‐Coated Organ‐on‐a‐Chip for Enhanced Precision in Preclinical Drug Testing
Tae Young Kim,
Jeong‐Won Choi,
Kijun Park
et al.
Abstract:In drug discovery, human organ‐on‐a‐chip (organ chip) technology has emerged as an essential tool for preclinical testing, offering a realistic representation of human physiology, real‐time monitoring, and disease modeling. Polydimethylsiloxane (PDMS) is commonly used in organ chip fabrication owing to its biocompatibility, flexibility, transparency, and ability to replicate features down to the nanoscale. However, the porous nature of PDMS leads to unintended absorption of small molecules, critically affectin… Show more
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