&lt;title&gt;Nonsensitized photoinduced destruction of tumor in experiments&lt;/title&gt;

Джагаров, Б. М.; Bizyuk, S. A.; Parkhats, Marina V.; Zhavrid, Edvard; Istomin, Yu. P.

doi:10.1117/12.640144

Cited by 3 publications

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“…Figures 2 and 3 show very typical photographs of the tumor slices, processed using the "Damage of Tumor" program and the proposed procedure. The dependence of the size of tumor necrosis on the conditions for irradiation of sensitized and nonsensitized tissues by light is discussed in more detail in [3][4][5]11]. In addition to the size of ne- crosis, we need to focus on the different types of destruction of the tumors depending on the irradiation conditions.…”

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Procedure for quantitative determination of effectiveness of photoinduced destruction of malignant tumors

Bizyuk

Istomin²,

Джагаров

2006

J Appl Spectrosc

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We have developed a procedure for analysis of the functional status of blood vessels in tumor tissues using computer-assisted color scanning of tumor slices and also for a quantitative assessment of the effectiveness of photoinduced destruction of tumor tissues in animal experiments. Its major advantage is direct determination of the size of the tumor necrosis zone. The procedure has been tested in an experiment on three strains of malignant tumors with different morphologies.

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“…Thus in a number of papers (see, for example, [3][4][5]) it has been shown that the spectrum of action for photodynamic therapy does not correspond to the absorption spectrum of the photosensitizer, while the dose-response dependence has * To whom correspondence should be addressed. 1 a shape which cannot be explained within the conventional scheme.…”

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confidence: 99%