&lt;title&gt;New optical probe designs for absolute (self-calibrating) NIR tissue hemoglobin measurements&lt;/title&gt;

Hueber, Dennis M.; Fantini, Sergio; Cerussi, Albert E.; Barbieri, Beniamino

doi:10.1117/12.356784

Cited by 80 publications

(102 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This also reveals why the NIRO system needs to have separations between the detectors (δ) much smaller than the SDS. The second terms in equations (18) and (19) Hueber et al (1999), this calculation of the absorption coefficient yields the same equation as used in the self-calibrating approach (equation (24)). …”

Section: Methods Used To Determine Concentration Changesmentioning

confidence: 94%

See 1 more Smart Citation

Measuring tissue hemodynamics and oxygenation by continuous-wave functional near-infrared spectroscopy—how robust are the different calculation methods against movement artifacts?

Scholkmann¹,

Metz

Wolf

2014

Physiol. Meas.

View full text Add to dashboard Cite

Continuous-wave near-infrared spectroscopy and imaging enable tissue hemodynamics and oxygenation to be determined non-invasively. Movements of the investigated subject can cause movement artifacts (MAs) in the recorded signals. The strength and type of MAs induced depend on the measurement principle. The aim of the present study was to investigate the quantitative relationship between different single-distance (SD) and multi-distance (MD) measurement methods and their susceptibility to MAs. We found that each method induces MAs to a different degree, and that MD methods are more robust against MAs than SD methods. AbstractContinuous-wave near-infrared spectroscopy and imaging enable tissue hemodynamics and oxygenation to be determined non-invasively. Movements of the investigated subject can cause movement artifacts (MAs) in the recorded signals. The strength and type of MAs induced depend on the measurement principle. The aim of the present study was to investigate the quantitative relationship between different single-distance (SD) and multi-distance (MD) measurement methods and their susceptibility to MAs. We found that each method induces MAs to a different degree, and that MD methods are more robust against MAs than SD methods.

show abstract

Section: Methods Used To Determine Concentration Changesmentioning

confidence: 94%

“…MD method 2: self-calibrating approach. In 1999, Hueber et al (1999) presented a further development of the SRS approach. For this method, at least two detectors (D 1 and D 2 ) and two sources (S 1 and S 2 ) are necessary ( figure 2(c)).…”

Section: Methods Used To Determine Concentration Changesmentioning

confidence: 99%

Measuring tissue hemodynamics and oxygenation by continuous-wave functional near-infrared spectroscopy—how robust are the different calculation methods against movement artifacts?

Scholkmann¹,

Metz

Wolf

2014

Physiol. Meas.

View full text Add to dashboard Cite

show abstract

“…While oxymetry systems from Hamamatsu Photonics (Hamamatsu, Japan) implement SRS (Matcher et al, 1995b;Suzuki et al, 1999), ISS Inc. uses the SC method (Hueber et al, 1999). Both approaches determine absolute values of StO 2 , but while the ISS system based on FD technology measures the μ s ′ and thus provides absolute values of [O 2 Hb], [HHb], [tHb] too, the SRS system has to assume a reasonable value for μ s ′.…”

Section: Multivariate Methods Of Typementioning

confidence: 99%

“…The SC approach (Hueber et al, 1999) enables to compensate for time varying differences in light coupling by employing at least two sources and two detectors, which are arranged symmetrically. Each source has a separation d L to one detector and d S to the other detector, with d L > d S .…”

Section: Multivariate Methods Of Typementioning

confidence: 99%

See 1 more Smart Citation

A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology

Scholkmann¹,

Kleiser²,

Metz³

et al. 2014

NeuroImage

1,481

1,394

View full text Add to dashboard Cite

This year marks the 20th anniversary of functional near-infrared spectroscopy and imaging (fNIRS/fNIRI). As the vast majority of commercial instruments developed until now are based on continuous wave technology, the aim of this publication is to review the current state of instrumentation and methodology of continuous wave fNIRI. For this purpose we provide an overview of the commercially available instruments and address instrumental aspects such as light sources, detectors and sensor arrangements. Methodological aspects, algorithms to calculate the concentrations of oxy-and deoxyhemoglobin and approaches for data analysis are also reviewed. From the single-location measurements of the early years, instrumentation has progressed to imaging initially in two dimensions (topography) and then three (tomography). The methods of analysis have also changed tremendously, from the simple modified Beer-Lambert law to sophisticated image reconstruction and data analysis methods used today. Due to these advances, fNIRI has become a modality that is widely used in neuroscience research and several manufacturers provide commercial instrumentation. It seems likely that fNIRI will become a clinical tool in the foreseeable future, which will enable diagnosis in single subjects. This year marks the 20th anniversary of functional near-infrared spectroscopy and imaging (fNIRS/fNIRI). As the vast majority of commercial instruments developed until now are based on continuous wave technology, the aim of this publication is to review the current state of instrumentation and methodology of continuous wave fNIRI. For this purpose we provide an overview of the commercially available instruments and address instrumental aspects such as light sources, detectors and sensor arrangements. Methodological aspects, algorithms to calculate the concentrations of oxy-and deoxyhemoglobin and approaches for data analysis are also reviewed. From the single-location measurements of the early years, instrumentation has progressed to imaging initially in two dimensions (topography) and then three (tomography). The methods of analysis have also changed tremendously, from the simple modified Beer-Lambert law to sophisticated image reconstruction and data analysis methods used today. Due to these advances, fNIRI has become a modality that is widely used in neuroscience research and several manufacturers provide commercial instrumentation. It seems likely that fNIRI will become a clinical tool in the foreseeable future, which will enable diagnosis in single subjects. Contents

show abstract

Phase dual‐slopes in frequency‐domain near‐infrared spectroscopy for enhanced sensitivity to brain tissue: First applications to human subjects

Blaney

Sassaroli

Pham

et al. 2019

Journal of Biophotonics

Self Cite

View full text Add to dashboard Cite

We present a first in vivo application of phase dual‐slopes (DSϕ), measured with frequency‐domain near‐infrared spectroscopy on four healthy human subjects, to demonstrate their enhanced sensitivity to cerebral hemodynamics. During arterial blood pressure oscillations elicited at a frequency of 0.1 Hz, we compare three different ways to analyze either intensity (I) or phase (ϕ) data collected on the subject's forehead at multiple source‐detector distances: Single‐distance, single‐slope and DS. Theoretical calculations based on diffusion theory show that the method with the deepest maximal sensitivity (at about 11 mm) is DSϕ. The in vivo results indicate a qualitative difference of phase data (especially DSϕ) and intensity data (especially single‐distance intensity [SDI]), which we assign to stronger contributions from scalp hemodynamics to SDI and from cortical hemodynamics to DSϕ. Our findings suggest that scalp hemodynamic oscillations may be dominated by blood volume dynamics, whereas cortical hemodynamics may be dominated by blood flow velocity dynamics.

show abstract

<title>New optical probe designs for absolute (self-calibrating) NIR tissue hemoglobin measurements</title>

Cited by 80 publications

References 15 publications

Measuring tissue hemodynamics and oxygenation by continuous-wave functional near-infrared spectroscopy—how robust are the different calculation methods against movement artifacts?

Measuring tissue hemodynamics and oxygenation by continuous-wave functional near-infrared spectroscopy—how robust are the different calculation methods against movement artifacts?

A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology

Phase dual‐slopes in frequency‐domain near‐infrared spectroscopy for enhanced sensitivity to brain tissue: First applications to human subjects

Contact Info

Product

Resources

About