<title>Laser investigation of metal ion adsorption on protein charge surface</title>

Physical Mechanisms of “Poisoning” the Living Organism by Heavy Metals

“…It was found earlier that cluster formation depends on metal ion radius [2][3][4]. Interaction of these ions with a protein surface involves, as a rule, their hydrated shells.…”

“…The PCS method was suggested to investigate the dynamic parameters of proteins in the aqueous solutions containing heavy metals [4,5]. The translational diffusion coefficient D t is described by the Stocks-Einstein-Debye formula as: In this formulae h  is viscosity, h r -hydrodynamic radius of the particle.…”

Phase transitions and precrystallization processes in a water–protein–electrolyte system

“…In this case, concentration heterogeneity in the form of a three-dimensional network arises due to the attraction potential [5]. Sometimes this heterogeneity is associated with protein clusters [10,11], microcoacervates [12] or various oligomers [13]. However, there is no agreement concerning the possible role of such structures in the crystallization mechanism [5,14,15].…”

“…Reduced to 15 1C effective thermodynamic parameters of HSA-SL WPM state versus NaCl concentration (m 3 ) and protein concentration (m 2 ) ratio as log(m 2 /m 3 ) in 0.001 M phosphate buffer, pH 7.3: (3,6,9,12)-DG (dotted lines); (1,5,8,11)-TDS (dashed lines) ; (2,4,7,10)-DH (solid lines).Protein concentration: (1,2,3)-50 mg/ml; (4,5,6)-100 mg/ml;(7,8,9)-150 mg/ml;(10,11,12)-200 mg/ml.…”

Volumetric properties and volumetric interaction parameters for the CsCl–monosaccharide (d-galactose, d-xylose and d-arabinose)–water systems at T=298.15 K

“…Monosaccharide is the modal compound of saccharide and has been regarded as a typical hydrophilic non-electrolyte resembling urea [2]. On the other hand, some researchers reported that rare alkali metal cesium was connected with many physiological processes, for example, the oxygen affinity in human red blood cells [3], the formation of macromolecular protein clusters [4,5] and the charge translocation by the Na þ /K þ -ATPase [6] were concerned with the existence of Cs þ . So the study of the interaction between CsCl and monosaccharides in water is valuable and helpful to understand the essence of some biological phenomena.…”