<title>Analytical modeling of spatial resolution curves in turbid media acquired with optical coherence tomography (OCT)</title>

Optical coherence tomography (OCT): a review

“…Consequently, they give little insight into the degradation of imaging quality that results from the multiple scattering effects. Although the importance of multiple scattering has been confirmed by several experimental studies carried out on tissue phantoms [33], [39], [40], an effective measure that quantifies loss of contrast and resolution in images of real tissue has not yet been found. To aid quantification of these effects, Lindmo et al [41] developed a Monte Carlo simulation method that permits direct visualization of the loss of focus that results from multiple scattering.…”

Mathematical Modeling of Optical Coherence Tomography

“…Then, the operators K 0 and M simplify to (27) and, recalling that M r;3 D 0 since p 3 D 0 (the polarization in the incident direction is zero),…”

“…(28). Now, the inversion of the operator K 0 given by (27) is performed considering the optical properties of the sample. …”

“…There exist several different approaches to model the propagation of light within the sample: the radiative transfer equation with scattering and absorption coefficients [9,38,45], Lambert-Beer's law with the attenuation coefficient [39,46], the equations of geometric optics with the refractive index [7], and Maxwell's equations with the susceptibility (or the refractive index) as optical parameters of the medium [6,12,27,37,43]. Also statistical approaches using Monte Carlo simulations are used [2,11,26,31,40].…”

Theoretical model for optical coherence tomography

“…As in Ref. 12,13the description for the propagation ofthe optical fields in the tissue is also based on the extended Huygens-Fresnel principle. In contrast to the Thrane's model 14 an imaginary lens proximal to the surface of sample is introduced that equivalently mimics the real focusing lens in the OCT system.…”