&lt;title&gt;All-fiber optic coherence domain interferometric techniques&lt;/title&gt;

Bush, Jeff; Davis, P.; Marcus, Michael A.

doi:10.1117/12.417430

Cited by 54 publications

(45 citation statements)

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“…A description of the scanning autocorrelator is described in reference 14 . The OCDR was integrated with a broadband high power superluminescent diode (SLD) (Denselight, Jessup, MD) with an output power of 45-mW and a bandwidth of 35-nm and a high-speed XY-scanning system (ESP 300 controller & 850G-HS stages, National Instruments, Austin, TX) for in vitro optical tomography.…”

Section: Polarization Sensitive Optical Coherence Tomography (Ps-oct)mentioning

confidence: 99%

Selective removal of natural occlusal caries by coupling near-infrared imaging with a CO 2 laser

Tao

Fried

2008

SPIE Proceedings

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Laser removal of dental hard tissue can be combined with optical, spectral or acoustic feedback systems to selectively ablate dental caries and restorative materials. Near-infrared (NIR) imaging has considerable potential for the optical discrimination of sound and demineralized tissue. Last year we successfully demonstrated that near-IR images can be used to guide a CO 2 laser ablation system for the selective removal of artificial caries lesions on smooth surfaces. The objective of this study was to test the hypothesis that two-dimensional near-infrared images of natural occlusal caries can be used to guide a CO 2 laser for selective removal. Two-dimensional NIR images were acquired at 1310-nm of extracted human molar teeth with occlusal caries. Polarization sensitive optical coherence tomography (PS-OCT) was also used to acquire depth-resolved images of the lesion areas. An imaging processing module was developed to analyze the NIR imaging output and generate optical maps that were used to guide a CO 2 laser to selectively remove the lesions at a uniform depth. Post-ablation NIR images were acquired to verify caries removal. Based on the analysis of the NIR images, caries lesions were selectively removed with a CO 2 laser while sound tissues were conserved. However, the removal rate varied markedly with the severity of decay and multiple passes were required for caries removal. These initial results are promising but indicate that the selective removal of natural caries is more challenging than the selective removal of artificial lesions due to varying tooth geometry, the highly variable organic/mineral ratio in natural lesions and more complicated lesion structure. Keywordsimage-guided laser ablation; near-infrared imaging; CO 2 laser; selective caries removal; polarization sensitive optical coherence tomography INTRODUCTIONNew optical caries imaging systems have been recently developed that are ideally suited to interface with lasers for the selective removal of dental caries. The most promising caries imaging systems employ fluorescence and near-IR imaging methods, including quantitative light fluorescence (QLF) 1 , near-IR fluorescence 2 , polarization sensitive-optical coherence tomography (PS-OCT) 3-5 and near-IR (NIR) imaging 4,6,7 . These imaging systems can be * daniel.fried@ucsf.edu, phone 415-502-6641, fax 415-476-0858. HHS Public Access Author ManuscriptAuthor Manuscript Author ManuscriptAuthor Manuscript used for the acquisition of 2-D or even 3-D images of tooth demineralization on proximal and occlusal surfaces. Lasers have been used for many years for industrial marking and computer aided design/machining (CAD/CAM) and high-speed scanning systems are in routine use. Other approaches involving acoustic and spectral feedback have already demonstrated that lasers can be scanned over tooth surfaces to remove dental composite and pigmented caries using acoustic and spectral feedback to differentiate these materials from sound enamel 8,9 . However, these approaches proved to be unsuccessful...

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Section: Polarization Sensitive Optical Coherence Tomography (Ps-oct)mentioning

confidence: 99%

Selective removal of natural occlusal caries by coupling near-infrared imaging with a CO 2 laser

Tao

Fried

2008

SPIE Proceedings

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“…A description of the scanning autocorrelator is described in reference 38 . The OCDR was integrated with a broadband high power superluminescent diode (SLD) (Denselight, Jessup, MD) with an output power of 45-mW and a bandwidth of 35-nm and a high-speed XY-scanning system (ESP 300 controller & 850G-HS stages, National Instruments, Austin, TX) for in vitro optical tomography.…”

Section: Ps-oct Systemmentioning

confidence: 99%

Imaging natural and artificial demineralization on dentin surfaces with polarization sensitive optical coherence tomography

2008

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The purpose of this study was to assess the potential of polarization sensitive optical coherence tomography (PS-OCT) to measure non-destructively the severity of natural and artificial caries lesions in dentin and determine the efficacy of intervention with anti-caries agents. Although several studies have demonstrated the utility of PS-OCT to image caries lesions in enamel and to quantify the lesion severity, only a few studies have focused on lesions in dentin. In this study images of natural root caries lesions on extracted human teeth were acquired with PS-OCT. In addition artificial lesions were produced in dentin after 12 days of exposure to a demineralization solution at a pH of 5.0. Before exposure, three incisions were made on the sample surfaces using Er:YAG laser irradiation and selected areas were treated with topical fluoride. PS-OCT images were acquired using a high power (45-mw) 1310-nm superluminescent diode with a bandwidth of 35-nm. PS-OCT was able to measure demineralization in dentin to a depth of ~ 1 mm. Polarized light microscopy and microradiography were used to measure lesion severity on histological thin sections for comparison. PS-OCT successfully measured the inhibition of demineralization by topical fluoride. Er:YAG laser irradiation did not significantly increase or decrease the rate of dentin demineralization. Keywords polarization; optical coherence tomography; Er:YAG laser; dentin; laser ablation; caries inhibition; thermal damage; topical fluoride INTRODUCTIONSeveral studies over the past few years have demonstrated that optical coherence tomography (OCT) can be used to measure natural and artificial caries lesions on enamel surfaces [1][2][3][4][5][6][7][8][9][10][11][12][13] . Although the penetration depth of near-IR light is considerably less in dentin than for enamel due to the higher scattering coefficient of dentin, PS-OCT and OCT images of dentin with root caries show that penetration depths of ~ 1 mm can be achieved and demineralized dentin can be discriminated from sound dentin and cementum 8,14 . * daniel.fried@ucsf.edu, 415-502-6641. HHS Public Access Author Manuscript Author ManuscriptAuthor Manuscript Author ManuscriptOptical coherence tomography (OCT) is a noninvasive technique for creating cross-sectional images of internal biological structure 15,16 . Depth-resolved measurements of caries lesions can be acquired on enamel surfaces [17][18][19][20][21] . In contrast to sound enamel that is highly transparent in the near-IR, sound dentin strongly scatters light in the near-IR and is highly birefringent. Therefore, there is some question whether the same approach employed to assess the severity of demineralization on enamel surfaces can be applied to the surface of dentin. We have shown that for enamel surfaces demineralized areas on the tooth depolarize incident linearly polarized light and the reflectivity in the (⊥) polarization state can be directly integrated to provide a measure of the lesion severity.PS-OCT is well-suited for imaging thermal changes...

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“…Progress in OCT imaging has come at both the system and component levels. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] This progress includes but is not limited to several advances: fabrication of new, broader light sources for achieving finer resolution (wavelength-swept source, ultra high-speed pulsed laser); building of faster spectrometers; development of compact twodimensional lateral scanning tools; design for miniaturized probes; manipulation and processing of various noises on the obtained images; optical control based on the OCT system; adaptive morphological imaging (polarization-sensitive OCT, Doppler OCT); functional imaging (blood flow, oxymetry, cell functions); additional fields of applications (clinical and non-clinical fields); and image processing for obtained images.…”

Section: Introductionmentioning

confidence: 99%

Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries

et al. 2012

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Abstract. The authors describe the development of an ultrafast three-dimensional (3D) optical coherence tomography (OCT) imaging system that provides real-time intraoperative video images of the surgical site to assist surgeons during microsurgical procedures. This system is based on a full-range complex conjugate free Fourierdomain OCT (FD-OCT). The system was built in a CPU-GPU heterogeneous computing architecture capable of video OCT image processing. The system displays at a maximum speed of 10 volume∕s for an image volume size of 160 × 80 × 1024 ðX × Y × ZÞ pixels. We have used this system to visualize and guide two prototypical microsurgical maneuvers: microvascular anastomosis of the rat femoral artery and ultramicrovascular isolation of the retinal arterioles of the bovine retina. Our preliminary experiments using 3D-OCT-guided microvascular anastomosis showed optimal visualization of the rat femoral artery (diameter < 0.8 mm), instruments, and suture material. Real-time intraoperative guidance helped facilitate precise suture placement due to optimized views of the vessel wall during anastomosis. Using the bovine retina as a model system, we have performed "ultra microvascular" feasibility studies by guiding handheld surgical micro-instruments to isolate retinal arterioles (diameter ∼0.1 mm). Isolation of the microvessels was confirmed by successfully passing a suture beneath the vessel in the 3D imaging environment.

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<title>All-fiber optic coherence domain interferometric techniques</title>

Cited by 54 publications

References 0 publications

Selective removal of natural occlusal caries by coupling near-infrared imaging with a CO 2 laser

Selective removal of natural occlusal caries by coupling near-infrared imaging with a CO 2 laser

Imaging natural and artificial demineralization on dentin surfaces with polarization sensitive optical coherence tomography

Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries

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