<strong>SYNTHESIS OF 2-AMINO-4<em>H</em>-PYRAN-3-CARBONITRILES ITS REACTION WITH CHLOROACETYL CHLORIDE</strong>

Abstract

Some 2-amino-4-aryl-3-cyano-5-ethoxycarbonyl-6-methyl-4H-pyrans were synthesized by reaction of by using three-component reaction included ethyl acetoacetate, malononitrile and appropriate substituted benzaldehydes. The role of different catalysts was examined, including organic and inorganic substances and ionic liquids. Some 2-amino-4Hpyran-3-carbonitriles were converted by reacting to chloroacetyl chloride. The structures of the obtained compounds were confirmed by the modern spectroscopic methods (IR, 1 H NMR, 13 C NMR).