<strong>New approach for the synthesis of pinane derived bisphosphines</strong>

Abstract

Abstract:The new approach to the synthesis of rigid bicyclic chiral bisphosphines derived from α-pinene is described. Thus, α-pinene is transformed into isopinocamphone or verbanone and these ketones are converted to spiro-epoxides. Controlled reduction of epoxides with borane gives allylic alcohols, which are transformed into bisphosphines by previously developed methods