<strong>Exploring BODIPY <em>meso</em>-enamines as singlet-oxygen photosensitizers for PDT</strong>

Abstract

The recent access to thecontrol of Vilsmeier-Haack reaction in BODIPYs has opened the selective generation of meso-enamines BODIPYs. meso-enamine functionalization deeply alters the photophysical properties of the BODIPY by quenching efficiently the fluorescence by the activation of non-radiative de-excitation channels, which in turn enables singlet-oxygen generation, and makes meso-enamine BODIPYs interesting as a possible new family of structurally-simple, easily-accessible and halogen-free singlet-oxygen photosensitizers for PDT. In this communication, we present the first study on the capability of a series of meso-enamines BODIPYs to generate singlet oxygen.