&lt;strong&gt;CBD-Supplemented Polishing Powder Enhances Tooth Polishing by Inhibiting Dental Plaque Bacteria &lt;/strong&gt;

Vasudevan, Kumar; Stahl, Veronica

doi:10.20944/preprints202007.0734.v1

Cited by 2 publications

(3 citation statements)

References 17 publications

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“…Solo el 17.1% de los estudios evaluaron el uso de endocannabinoides. Por su parte, de los 7 estudios clínicos incluidos, 2 de ellos mencionan como terapéuticas el uso de productos comerciales 13,15 , 4 reportan el uso de productos experimentales [16][17][18][19] , mientras el restante no describe claramente un producto específico empleado ni su concentración 20 .…”

Section: Características De Los Estudiosunclassified

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Cannabinoid medicine in the orofacial region: status and prospects

Mederos,

Francia

2023

Odontol Sanmarquina

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Introduction: The interest in using cannabis and cannabinoids as a therapeutic tool has gained relevance in medicine in recent years. In line with this, interest in its study has increased in dentistry. The aim of the present narrative review was to analyze and synthesize the available information about the current therapeutic possibilities of cannabis in dentistry and its future perspectives. Materials and methods: an electronic search conducted that included articles until December 2022, in the MEDLINE, Scopus, Scielo and Google Scholar databases. The following main keywords used: “dental,” “dentistry,” “cannabis,” “cannabinoids,” “benefits,” “therapeutics,” “treatment,” “potential.” A total of 834 records founded in the first searches. Forty-five full-text articles assessed for eligibility. Thirty-five studies included for the qualitative analysis of the present review. Results: Studies show a great variability of cannabinoids and derivatives used, including commercial preparations, as well as experimental preparations. In vitro, in vivo, and clinical studies had conducted evaluating the action of cannabinoids in the control of orofacial pain, as anti-inflammatory and healing, in bone tissue regeneration, as antimicrobial and evaluating their anti-cancer ability. Conclusions: Cannabinoids have shown potential in the treatment of various oral conditions and/or disorders. Even the standardization of products and treatment protocols is insufficient, which is why more studies are necessary to evaluate presentations, derivatives, extraction methods, concentrations, and routes of administration for their best use.

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Section: Características De Los Estudiosunclassified

“…El estudio clínico de intervención estudió la suplementación con cannabidiol de pasta para profilaxis 19 . Mediante el análisis in vitro de las muestras de placa obtenidas, se encontró una reducción significativa en el número de UFC en comparación con una pasta sin el agregado de CBD.…”

Section: Acción Antimicrobianaunclassified

Cannabinoid medicine in the orofacial region: status and prospects

Mederos,

Francia

2023

Odontol Sanmarquina

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“…Interestingly, the preparations were alcohol-free and exhibited similar efficacy to 0.2% chlorhexidine. The same research group has suggested that the incorporation of CBD into dental polish can assist in plaque removal [ 92 ]. On the other hand, also in the oral context, Gu et al have shown that cannabinoids, including CBD, exhibit differential activities against common bacterial components of dental plaque.…”

Section: Translational Considerations For the Development Of Cannabis...mentioning

confidence: 99%

The Antimicrobial Properties of Cannabis and Cannabis-Derived Compounds and Relevance to CB2-Targeted Neurodegenerative Therapeutics

et al. 2022

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Cannabinoid receptor 2 (CB2) is of interest as a much-needed target for the treatment or prevention of several neurogenerative diseases. However, CB2 agonists, particularly phytocannabinoids, have been ascribed antimicrobial properties and are associated with the induction of microbiome compositional fluxes. When developing novel CB2 therapeutics, CB2 engagement and antimicrobial functions should both be considered. This review summarizes those cannabinoids and cannabis-informed molecules and preparations (CIMPs) that show promise as microbicidal agents, with a particular focus on the most recent developments. CIMP–microbe interactions and anti-microbial mechanisms are discussed, while the major knowledge gaps and barriers to translation are presented. Further research into CIMPs may proffer novel direct or adjunctive strategies to augment the currently available antimicrobial armory. The clinical promise of CIMPs as antimicrobials, however, remains unrealized. Nevertheless, the microbicidal effects ascribed to several CB2 receptor-agonists should be considered when designing therapeutic approaches for neurocognitive and other disorders, particularly in cases where such regimens are to be long-term. To this end, the potential development of CB2 agonists lacking antimicrobial properties is also discussed.

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<strong>CBD-Supplemented Polishing Powder Enhances Tooth Polishing by Inhibiting Dental Plaque Bacteria </strong>

Cited by 2 publications

References 17 publications

Cannabinoid medicine in the orofacial region: status and prospects

Cannabinoid medicine in the orofacial region: status and prospects

The Antimicrobial Properties of Cannabis and Cannabis-Derived Compounds and Relevance to CB2-Targeted Neurodegenerative Therapeutics

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