<p>Work Loss in Relation to Pharmacological and Surgical Treatment for Crohn’s Disease: A Population-Based Cohort Study</p>

Abstract

Purpose: Patients with Crohn's disease have increased work loss. We aimed to describe changes in work ability in relation to pharmacological and surgical treatments.

A nationwide cohort study of the incidence of inflammatory bowel disease in Sweden from 1990 to 2014

“…We reported a lifetime risk of IBD of 2.5% for males and females, supporting previous findings of a considerable burden of disease and health care use of IBD patients in Sweden 35,36 …”

“…We reported a lifetime risk of IBD of 2.5% for males and females, supporting previous findings of a considerable burden of disease and health care use of IBD patients in Sweden. 35,36 In conclusion, we found evidence of an increased incidence of IBD overall and by subtype in both males and females during the 1990-2014 study period. However, a temporal increase up until 2001 was followed by a decrease in the IBD, UC and CD IRs from 2002 onwards.…”

“…IBD is characterised by chronic and relapsing inflammation of the gastrointestinal tract, often diagnosed at a young age 2,3 . The disease is associated with reduced quality of life, loss of work productivity and increased morbidity and mortality 4‐7 …”

Prospective observational study on Stelara (ustekinumab) assessing effectiveness in Crohn’s disease (PROSE): a 16-week follow-up

“…The disease is becoming increasingly common worldwide, with more than 20,000 affected individuals in Sweden only [2]. Diagnosis is often at a young age, and the disease course is associated with loss of work productivity, increased morbidity and mortality [2][3][4][5]. To minimise disease progression, treatment algorithms of CD aim to induce and maintain remission [6].…”

Letter: is unrealised adult height resulting from paediatric Crohn’s disease associated with a potential reduction in lifetime earnings? Authors’ reply

“…To what extent this difference also results in future lost life chances (eg not as good educational results and less well‐paid employments as would have been expected) and reduction in lifetime earnings is yet to be shown. More importantly, many studies have also shown that patients with IBD, regardless of age of diagnosis, have more work loss (sick leave and disability pension) than matched reference individuals or IBD‐free siblings 4‐9 ; these observations to us suggests that it is the disease itself, with its remitting and relapsing disease course, rather than the (limited) reduction in adult height that causes reduced lifetime earnings. That is, if lifetime earnings are indeed reduced, which is yet to be shown (although we agree it is likely).…”