&lt;p&gt;Surface Engineering of Metal–Organic Framework as pH-/NIR-Responsive Nanocarrier for Imaging-Guided Chemo-Photothermal Therapy&lt;/p&gt;

Guo, Haibin; Xia, Yaoyao; Feng, Ke; Qu, Xiaowei; Zhang, Cuilian; Wan, Feng

doi:10.2147/ijn.s239910

Cited by 29 publications

(9 citation statements)

References 45 publications

(47 reference statements)

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“…It just needs to dissolve dopamine monomer with core nanomaterials in an alkaline environment and to be exposed to air to obtain the nano‐complexes, [28,47] which integrate the physicochemical properties of every single material. Considerable attention has also been paid to effective drug delivery and controlled drug release of PDA NPs in CT, regulated by the external stimulus (near‐infrared laser) and internal stimulation (glutathione, GSH) triggered degradation of PDA [48,49] …”

Section: The Properties Of Pdamentioning

confidence: 99%

Polydopamine‐Based Nanoparticles for Photothermal Therapy/Chemotherapy and their Synergistic Therapy with Autophagy Inhibitor to Promote Antitumor Treatment

Lü

Cai

Dai

et al. 2021

The Chemical Record

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Polydopamine (PDA) has attracted much attention recently due to its strong adhesion capability to most substrates. After combining with organic (such as organic metal framework, micelles, hydrogel, polypeptide copolymer) or inorganic nanomaterials (such as gold, silicon, carbon), polydopamine‐based nanoparticles (PDA NPs) exhibit the merging of characteristics. Until now, the preparation methods, polymerization mechanism, and photothermal therapy (PTT) or chemotherapy (CT) applications of PDA NPs have been reported detailly. Since the PTT or CT treatment process is often accompanied by exogenous stimuli, tumor cells usually induce pro‐survival autophagy to protect the cells from further damage, which will weaken the therapeutic effect. Therefore, an in‐depth understanding of PDA NPs modulated PTT, CT, and autophagy is required. However, this association is rarely reviewed. Herein, we briefly described the relationship between PTT/CT, autophagy, and tumor treatment. Then, the outstanding performances of PDA NPs in PTT/CT and their combination with autophagy inhibitors for tumor synergistic therapy have been summarized. This work is expected to shed light on the multi‐strategy antitumor therapy applications of PDA NPs.

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Section: The Properties Of Pdamentioning

confidence: 99%

Polydopamine‐Based Nanoparticles for Photothermal Therapy/Chemotherapy and their Synergistic Therapy with Autophagy Inhibitor to Promote Antitumor Treatment

Lü

Cai

Dai

et al. 2021

The Chemical Record

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“…Under NIR laser irradiation, the resultant ZIF-8/ DMPP showed a satisfactory thermal effect, which accelerated the release of DOX and augmented the chemotherapy. Meanwhile, the chelation of Mn ions onto PDA shells made this system possible for MRI/PAI, which was proved by both in vitro and in vivo results (Guo et al, 2020).…”

Section: Theranosticsmentioning

confidence: 90%

Metal-Organic Frameworks and Their Composites Towards Biomedical Applications

Cui

et al. 2021

Front. Mol. Biosci.

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Owing to their unique features, including high cargo loading, biodegradability, and tailorability, metal–organic frameworks (MOFs) and their composites have attracted increasing attention in various fields. In this review, application strategies of MOFs and their composites in nanomedicine with emphasis on their functions are presented, from drug delivery, therapeutic agents for different diseases, and imaging contrast agents to sensor nanoreactors. Applications of MOF derivatives in nanomedicine are also introduced. Besides, we summarize different functionalities related to MOFs, which include targeting strategy, biomimetic modification, responsive moieties, and other functional decorations. Finally, challenges and prospects are highlighted about MOFs in future applications.

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“…Most PTAs can be used for PAI [ 30 ], where light energy is converted into heat energy by laser irradiation, causing local tissue expansion to generate pressure waves that produce photoacoustic signals. Guo et al grew a polydopamine (PDA) shell layer on the surface of ZIF–8 wrapped with DOX and modified with Mn 2+ and PEG [ 31 ]. Mn 2+ is commonly regarded as an MRI contrast agent, whereas PDA is widely used for photothermal therapy (PTT) and PAI due to its good photothermal conversion rate.…”

Section: Biomedical Imagingmentioning

confidence: 99%

Nanoscale Zeolitic Imidazolate Framework (ZIF)–8 in Cancer Theranostics: Current Challenges and Prospects

Xie

Liu

Huang

et al. 2022

Cancers

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Cancer severely threatens human health and has remained the leading cause of disease–related death for decades. With the rapid advancement of nanomedicine, nanoscale metal–organic frameworks are believed to be potentially applied in the treatment and biomedical imaging for various tumors. Zeolite imidazole framework (ZIF)–8 attracts increasing attention due to its high porosity, large specific surface area, and pH–responsiveness. The designs and modifications of ZIF–8 nanoparticles, as well as the strategy of drug loading, demand a multifaceted and comprehensive understanding of nanomaterial features and tumor characteristics. We searched for studies on ZIF–8–based nanoplatforms in tumor theranostics on Web of Science from 2015 to 2022, mainly focused on the research published in the past 3 years, summarized the progress of their applications in tumor imaging and treatment, and discussed the favorable aspects of ZIF–8 nanoparticles for tumor theranostics as well as the future opportunities and potential challenges. As a kind of metal–organic framework material full of potential, ZIF–8 can be expected to be combined with more therapeutic systems in the future and continue to contribute to all aspects of tumor therapy and diagnosis.

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<p>Surface Engineering of Metal–Organic Framework as pH-/NIR-Responsive Nanocarrier for Imaging-Guided Chemo-Photothermal Therapy</p>

Cited by 29 publications

References 45 publications

Polydopamine‐Based Nanoparticles for Photothermal Therapy/Chemotherapy and their Synergistic Therapy with Autophagy Inhibitor to Promote Antitumor Treatment

Polydopamine‐Based Nanoparticles for Photothermal Therapy/Chemotherapy and their Synergistic Therapy with Autophagy Inhibitor to Promote Antitumor Treatment

Metal-Organic Frameworks and Their Composites Towards Biomedical Applications

Nanoscale Zeolitic Imidazolate Framework (ZIF)–8 in Cancer Theranostics: Current Challenges and Prospects

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