&lt;p&gt;Short-Term Quality of Life, Functional Status, and Their Predictors in Tongue Cancer Patients After Anterolateral Thigh Free Flap Reconstruction: A Single-Center, Prospective, Comparative Study&lt;/p&gt;

Tamer, Roba; Chen, Yongyi; Xu, Xianghua; Xie, Changqing; Swai, Joel

doi:10.2147/cmar.s268912

Cited by 8 publications

(25 citation statements)

References 32 publications

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“…13 We have compared the results of our study with those quoted in the literature (Table S3). 5,[12][13][14][15][16][17][18] Manrique et al performed a systematic review and meta-analysis on the speech and swallowing outcomes following a major glossectomy. 6 Their study also included published literature on total glossectomy with laryngeal preservation.…”

Section: Discussionmentioning

confidence: 99%

“…17,18 Our thorough literature review could identify the use of validated QoL and swallowing scales in patients undergoing either partial or hemiglossectomy or total glossectomy with laryngeal preservation. 12,14 Previously published studies focusing on QoL in major glossectomies have considered NG tube dependence and decannulation rates to be proxy indicators for QoL and swallowing. 6 Contrary to such a belief our study shows that though MDADI was found to have good concordance with the functional swallowing outcome, there was a negative correlation between post-treatment FACT-HN and PAS scores, indicating that mere absence of dysphagia and aspiration did not necessarily translate into better QoL.…”

Section: Discussionmentioning

confidence: 99%

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Quality of life and swallowing outcomes following major glossectomy: A prospective single‐center experience

Mitra,

Panda,

Thakar

et al. 2023

Head & Neck

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BackgroundThere exists a lacuna in the structured reporting of swallowing dysfunction and quality of life (QoL) outcome following major glossectomy.MethodsProspective cohort study to assess the swallowing dysfunction and QoL following STG (subtotal glossectomy) or NTG (near total glossectomy) over a 6‐month period using FEES and PAS scale, MDADI, and FACT‐HN.ResultsTwenty‐four patients were available for analysis. The pre‐ and post‐adjuvant evaluation revealed a statistically significant improvement in the composite MDADI and FACT‐HN scores. Subscale analysis of FACT‐HN scores revealed maximum deficit in the head and neck cancer‐specific score domain followed by functional domain and social well‐being domain, with serial improvement noted in the post‐adjuvant setting.ConclusionThis study showed serial improvement in terms of swallowing dysfunction although social and functional well‐being domains related to QoL continued to reveal major deficits. Better outcomes were seen with preservation of bilateral base of tongue and mandible.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Quality of life and swallowing outcomes following major glossectomy: A prospective single‐center experience

Mitra,

Panda,

Thakar

et al. 2023

Head & Neck

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show abstract

“…28 In addition, ALTF is superior in terms of being an adequately sized flap, sparing major vasculature, and having better cosmesis at both donor and recipient sites. 29 Other studies reported that the donor site complications of the anterolateral thigh valve are rare compared with radial forearm free flap. 8,18 This modified ALTF is more suitable for older patients while younger patients usually use bony flap to realize implant-denture restoration.…”

Section: Discussionmentioning

confidence: 99%

Modified Reconstruction of Brown II Defects With Anterolateral Thigh Flaps Following Tumor Resection

Zeng

Tao

Liu

et al. 2022

Journal of Craniofacial Surgery

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significant difference in tumor incidence in our study as to patients' gender, although female patients slightly predominated with 50.7%, as in studies. [9][10][11][12] The age of patients in our study ranged from 9 to 84 years (mean 54.1 ± 14.83). There was a statistically significant higher incidence of malignant tumors in older patients. 8,10,13,14 As to tumor localization, the parotid gland is the most commonly affected; our study showed that MSGs were the most common localization (83.56%), and the parotid gland was most commonly affected with 692 cases (76.3% of salivary gland tumors). 1,10 12,14,16 MSG tumors were most commonly benign (87.07%). MiSG sites are the most commonly affected after the parotid gland, followed by the submandibular and sublingual glands. 1,4,[8][9][10][11][12]14,16,18,19 Our study's most common MiSG site was the oral cavity, followed by the nasal cavity and paranasal sinuses; the larynx was the rarest MiSG site.Submandibular gland tumors comprised 7.06% of all salivary tumors in our series. Salivary gland tumors are sporadic in the sublingual gland and are most exclusively malignant. 1,8 Various studies report that the submandibular gland was affected in 17% to 23% and MiSG sites in 14% to 22%. 10,18 MiSG tumors represented 16.4% of salivary glands tumors in our study, whereas other studies do not report MiSG tumors. 8,9,17 Sublingual gland tumors incidence was reported at 0.4% to 3.2%. 14,17 Our study reports 0.20% of salivary tumors in the sublingual gland.Papers from different geographic regions show that most salivary gland tumors are benign, ranging from 64.2% to71.5%, 8,10,19 and of these, the most common is pleomorphic adenoma. The majority of parotid tumors are benign, with pleomorphic adenoma and Warthin tumor being the most common. 1,

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“…Roba et al reported that the quality of life and functional status of tongue cancer patients 1 month after surgery were worse than those before surgery and 3 months after surgery. 10 A systematic review noted that speech and swallowing functions showed a significant decline at the early postoperative (1 month) stage in tongue cancer patients. 11 There was also evidence that head and neck cancer patients receiving radiotherapy and chemotherapy suffered from the heaviest symptom burden in the treatment phase, whereas those treated with surgery experienced the heaviest symptom burden at 3-9 days postsurgery.…”

Section: Introductionmentioning

confidence: 99%

Perioperative symptom burden and its influencing factors in patients with oral cancer: A longitudinal study

Wang

Chen

et al. 2022

Asia-Pacific Journal of Oncology Nursing

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<p>Short-Term Quality of Life, Functional Status, and Their Predictors in Tongue Cancer Patients After Anterolateral Thigh Free Flap Reconstruction: A Single-Center, Prospective, Comparative Study</p>

Cited by 8 publications

References 32 publications

Quality of life and swallowing outcomes following major glossectomy: A prospective single‐center experience

Quality of life and swallowing outcomes following major glossectomy: A prospective single‐center experience

Modified Reconstruction of Brown II Defects With Anterolateral Thigh Flaps Following Tumor Resection

Perioperative symptom burden and its influencing factors in patients with oral cancer: A longitudinal study

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