&lt;p&gt;Remote Patient Monitoring for the Detection of COPD Exacerbations&lt;/p&gt;

Cooper, Christopher B.; Sirichana, Worawan; Arnold, Michael L.; Neufeld, Eric V.; Taylor, Michael; Wang, Xiaoyan; Dolezal, Brett A.

doi:10.2147/copd.s256907

Cited by 16 publications

(12 citation statements)

References 33 publications

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“…Given the impact of physical activity on the autonomic function, monitoring and quantifying the health status and physical activity of patients with COPD at home might play a crucial role for reducing their future risk. Early recognition of patients’ abnormal physiological parameters might be relevant to guide appropriate interventions and reduce healthcare utilization in patients with COPD [ 48 ], as well as optimizing quality of life [ 49 ]. For this purpose, wearable devices have the potential of continuously collecting objective and clinically meaningful data from patients at a reduced cost [ 50 ].…”

Section: Discussionmentioning

confidence: 99%

Use of a Wearable Biosensor to Study Heart Rate Variability in Chronic Obstructive Pulmonary Disease and Its Relationship to Disease Severity

Park

Saiphoklang

Jung

et al. 2022

Sensors

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The purpose of this study was to explore the relationships between heart rate variability (HRV) and various phenotypic measures that relate to health and functional status in chronic obstructive pulmonary disease (COPD), and secondly, to demonstrate the feasibility of ascertaining HRV via a chest-worn wearable biosensor in COPD patients. HRV analysis was performed using SDNN (standard deviation of the mean of all normal R-R intervals), low frequency (LF), high frequency (HF), and LF/HF ratio. We evaluated the associations between HRV and COPD severity, class of bronchodilator therapy prescribed, and patient reported outcomes. Seventy-nine participants with COPD were enrolled. There were no differences in SDNN, HF, and LF/HF ratio according to COPD severity. The SDNN in participants treated with concurrent beta-agonists and muscarinic antagonists was lower than that in other participants after adjusting heart rate (beta coefficient −3.980, p = 0.019). The SDNN was positively correlated with Veterans Specific Activity Questionnaire (VSAQ) score (r = 0.308, p = 0.006) and handgrip strength (r = 0.285, p = 0.011), and negatively correlated with dyspnea by modified Medical Research Council (mMRC) questionnaire (r = −0.234, p = 0.039), health status by Saint George’s Respiratory Questionnaire (SGRQ) (r = −0.298, p = 0.008), symptoms by COPD Assessment Test (CAT) (r = −0.280, p = 0.012), and BODE index (r = −0.269, p = 0.020). When measured by a chest-worn wearable device, reduced HRV was observed in COPD participants receiving inhaled beta-sympathomimetic agonist and muscarinic antagonists. HRV was also correlated with various health status and performance measures.

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Section: Discussionmentioning

confidence: 99%

Use of a Wearable Biosensor to Study Heart Rate Variability in Chronic Obstructive Pulmonary Disease and Its Relationship to Disease Severity

Park

Saiphoklang

Jung

et al. 2022

Sensors

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“…Combining self-reported symptoms with day-to-day physiological measurements can help to provide a more detailed picture on the occurrence of exacerbations. However, this is labor-intensive for the patients, as well for the health-care professional ( 11 , 17 ).…”

Section: Discussionmentioning

confidence: 99%

Can COPD Exacerbations Be Picked Up Early via a Weekly Medication Question Through a Smartphone Application?

Blondeel

Demeyer

Breuls

et al. 2022

Front. Rehabilit. Sci.

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BackgroundExacerbations affect the disease trajectory of patients with COPD and result in an acute drop of functional status and physical activity. Timely detection of exacerbations by non-medical healthcare professionals is needed to counteract this decline. The use of digital health applications in patient interaction allows embedded detection of exacerbations. However, it is unknown if this is an effective way to pick up exacerbations.MethodWe investigated the detection of exacerbations in patients with COPD enrolled in a physical activity coaching program, by prompting a weekly question on changes in medication via the smartphone application. Data on response rate and occurrence of exacerbations were collected.ResultsResponse rate to the medication question, evaluated in 42 patients, was 72% (n = 497). A change in medication was reported through the smartphone application in 38 (7.6%) of the answered questions. The response rate was significantly lower at 6 months follow-up compared to the first month (p =0.03). When evaluating the occurrence of adverse events in a subset of patients who completed 6 months of follow-up (n = 27), 18 exacerbations were registered in eight patients, of which 10 of these exacerbations (56%) were picked up by the medication question in the coaching application.ConclusionElectronic interaction through a weekly medication question, embedded in a smartphone application, is feasible to support the detection of the occurrence of COPD exacerbations and can be used complementary to regular forms of detecting exacerbations. Compliance and smartphone literacy should be optimized when further using this method to report on COPD exacerbations.

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“…Overall, in patients with COPD, peak expiratory flow is likely not reliable given its increased variability and possibility of pressure-dependent airway collapse in this population 35. Similar to spirometry, changes in PEFR are discordant with changes in symptoms or other measures of exacerbation 23. While PEFR has been studied only in a few trials, the trend of this data suggests it has low utility in RPM.…”

Section: Patient Monitoringmentioning

confidence: 99%

Remote Patient Monitoring in the Management of Chronic Obstructive Pulmonary Disease

Chalupsky

Craddock

Schivo

et al. 2022

Journal of Investigative Medicine

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Remote patient monitoring allows monitoring high-risk patients through implementation of an expanding number of technologies in coordination with a healthcare team to augment care, with the potential to provide early detection of exacerbation, prompt access to therapy and clinical services, and ultimately improved patient outcomes and decreased healthcare utilization.In this review, we describe the application of remote patient monitoring in chronic obstructive pulmonary disease including the potential benefits and possible barriers to implementation both for the individual and the healthcare system.

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<p>Remote Patient Monitoring for the Detection of COPD Exacerbations</p>

Cited by 16 publications

References 33 publications

Use of a Wearable Biosensor to Study Heart Rate Variability in Chronic Obstructive Pulmonary Disease and Its Relationship to Disease Severity

Use of a Wearable Biosensor to Study Heart Rate Variability in Chronic Obstructive Pulmonary Disease and Its Relationship to Disease Severity

Can COPD Exacerbations Be Picked Up Early via a Weekly Medication Question Through a Smartphone Application?

Remote Patient Monitoring in the Management of Chronic Obstructive Pulmonary Disease

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