<p>Prevalence of Diabetes Mellitus, Prediabetes and Its Associated Factors in Dessie Town, Northeast Ethiopia: A Community-Based Study</p>

Abstract

Background: Diabetes mellitus is becoming an epidemic public health problem in developing countries such as Ethiopia. As the International Diabetes Federation indicates, the number of adults living with diabetes globally has been increasing from time to time. If early screening and follow-up are done, diabetes is a manageable disease. However, diabetes study at the community level in Ethiopia is limited and scarce. Therefore, the present study was conducted to assess the current prevalence of DM, prediabetes and its associated factors in Dessie Town, Northeast Ethiopia. Methods: A community-based cross-sectional study was conducted from January to March 2019 among people aged 18 years and above in Dessie Town, Northeast Ethiopia. A multistage sampling technique was used to select a total of 587 study participants. Sociodemographic and behavioral characteristic data were collected using a pretested semistructured questionnaire. Venous blood samples were used to determine the level of blood glucose and lipid profile. Diagnosis and classification of diabetes mellitus and prediabetes were based on the criteria of the American Diabetes Association. Results: The prevalence of diabetes mellitus and prediabetes was 6.8% (95% CI 4.9-9.0) and 15.7% (95% CI 12.9-18.7), respectively. The prevalence of previously undiagnosed diabetes mellitus was 72.5%. Positive family history of diabetes mellitus (AOR: 20.24, 95% CI 4.74-86.43), smoking habit (AOR: 12.12, 95% CI 2.30-63.73), overweight (AOR: 21.95, 95% CI 6.73-71.603), systolic hypertension (AOR: 4.61, 95% CI 1.09-19.50) and hypercholesterolemia (AOR: 8.97, 95% CI 2.05-39.23) were significantly associated with diabetes mellitus. Prediabetes was associated with advanced age (AOR: 3.55, 95% CI 1.16-10.79), marital status (single) (AOR: 3.06, 95% CI 1.40-6.67), educational status (illiterate) (AOR: 2.35, 95% CI 1.04-5.35) and overweight (AOR: 2.11, 95% CI 1.05-4.23). Conclusion: There was a higher prevalence of diabetes mellitus and prediabetes. In addition, the prevalence of undiagnosed diabetes mellitus was high in our study area. Therefore, targeting the control and prevention strategy to such modifiable risk factors associated with diabetes and prediabetes may contribute to the reduction of the prevalence and further complications of diabetes mellitus.

Prevalence of prediabetes and related cardiovascular risk factors among Employees of Ayder Comprehensive Specialized Hospital, Tigray, Northern Ethiopia

“…The exceedingly higher prevalence in the later study is due to the fact that the study was carried out among professionals who had high risk scores for diabetes. On the other hand the current result is similar with the findings found from population studies in Ethiopia (26,27), Northeast China(28),…”

<p>Prevalence of Diabetes Mellitus and Associated Factors in Addis Ababa Public Health Facilities, Addis Ababa, Ethiopia, 2016</p>

“…The prevalence of diabetes mellitus in this study was 14.8%, which was higher than the studies in North West Ethiopia (5.1%), 8 in central Ethiopia (6.5%), 13 East Shoa of Ethiopia (5%), 14 and Northern Ethiopia (1.3%). 12 The finding from this study was also higher than findings from a community-based study in Southern Ethiopia (1.9%), 18 institution-based study in Addis Ababa (2.6%), 19 20.90% 66.70% and Dessie town, Northeast Ethiopia (6.8%), 20 and Mizan Aman Town, Southwest Ethiopia, (6.5%). 21 The prevalence of undiagnosed diabetes in Bahir Dar city, northwest Ethiopia was 10.2%, 22 which was slightly lower than the findings of the current study whilst the current study was consistent with the study in Spain (13.8%), 6 and Tanzania (12%).…”

“…19 Ever checked blood glucose level (AOR=1.91, 95% CI 1.03 to 3.51), family history of DM (AOR=2.5, 95% CI 1.21 to 5.18), do not know the symptoms of diabetes (AOR=2.06, 95% CI 1.08 to 3.89), body mass index (BMI) >25 kg/m2 (AOR=1.98, 95% CI 1.09 to 3.60) were factors associated with diabetes. 22 20 Waist circumference smoking habits, hypertension, total cholesterol level, and body mass index were factors significantly associated with diabetes. 21 Family history of diabetes, older age, and physical inactivity were significantly associated with diabetes among urban population while alcohol consumption was inversely associated with diabetes mellitus in a rural population.…”

Diabetes mellitus and its associated risk factors in patients with human immunodeficiency virus on anti-retroviral therapy at referral hospitals of Northwest Ethiopia

“…The estimated prevalence in this study is significantly higher than the 2019 IDF report (ninth edition) of national prevalence (3.2%) of diabetes in Ethiopian adult (20-79 years) population [28] and the 2016 WHO report of the national prevalence (3.8%) of diabetes in the general population of Ethiopia [29]. It is also higher than the diabetes prevalence (6.8%) report of a community-based cross-sectional study conducted in 2019 in northeast Ethiopia [30] as well as a meta-analysis report (4.99%) for Ethiopia population [31]. The higher prevalence has been supported by different studies [12,[32][33][34] indicating that HIV increases the risk of developing a number of health problems [35].…”