<p>Most Adult Intussusceptions are Caused by Tumors: A Single-Centre Analysis</p>

Abstract

Background: Adult intussusception is less common than paediatric intussusception. The aim of this study was to explore the clinical presentation, aetiology, diagnosis and treatment of adult intussusception. Methods: Adults (>18 years) with intussusception treated by surgical or conservative measures were included from January 2005 to January 2018, and the manifestation, types, diagnosis and treatment of adult intussusception in our centre were reviewed. Results: A total of 150 patients with adult intussusception were included in this study. The clinical manifestations included 111 cases (74%) of abdominal pain, 38 cases (25.3%) of bloody stool, 37 cases (24.7%) of bowel obstructions, 33 cases (22%) of abdominal distension, 29 cases (19.3%) of nausea and vomiting, 19 cases (12.7%) of an abdominal mass, and 12 cases (8.0%) of diarrhoea. The types of intussusception were classified into 36 cases (24%) of enteric intussusception, 87 cases (58%) of intestine-colon intussusception and 27 cases (18%) of colonic intussusception. Surgical intervention was applied in 139 cases (92.7%), including 115 patients who underwent open surgery, and laparoscopy-assisted surgery was performed in 24 patients. The main pathogenesis of intussusception was malignant tumors in 51 cases (36.7%) and benign tumors and polyps in 49 cases (35.3%). Conclusion: Malignant and benign tumors are the main causes of adult intussusception. Abdominal CT is the preferred evaluation method for the preoperative diagnosis of this condition. The choice of surgical procedure depends on the location and type of intussusception.

Surgical treatments of recurrent small intestine metastatic melanoma manifesting with gastrointestinal hemorrhage and intussusception: A case report

“…Our patient presented with melena and intussusception. Tumors are the primary cause of intussusception in adults[ 7 ]. The tumors causing this abnormality are primarily benign.…”

“…Even though small intestine metastases are a rare and life-threatening clinical entity, they occur more frequently than primary small intestine tumors[ 6 ]. A recent study found that tumors are the primary causes of intussusception in adults[ 7 ]. Intussusception is the invagination of a segment of the gastrointestinal tract into an immediately adjacent area.…”

Jejunal Lipoma Causing Intussusception in an Adult

“…Colonic intussusceptions in adults are induced by malignancy as the lead point in 60% of cases, while only 30% of small bowel intussusceptions are caused by malignant tumours. [7][8][9] Benign causes of small bowel intussusception are predominantly diverticular disease (Meckel's) and polyps of various origins. Lipomas are rarely encountered and comprise only 1% of all gastrointestinal tumours.…”

Mucinous tumor of transverse colon presenting with colo-colic intussusception in a 24-year old female: Aggressive tumor with a rare presentation in a young female

“…Intussusception is the most common cause of bowel obstruction in the pediatric population [1][2][3][4][5]. Intussusception is rare in adults with an estimated incidence of 2 cases/1,000,000 population/year, accounting for only 5% of all intussusceptions, 1% of all bowel obstructions, and 0.003-0.02% of all hospital admissions [2][3][4][5][6][7][8][9]. Amongst the Adult Intussusceptions (AI), 38-44% occur in the colon and 52-55% in the small intestine [4,6].…”

“…Due to this variable presentation, AI is difficult to diagnose, despite the evolution of imaging procedures and often remains unrecognized or misdiagnosed prior to surgery [2,5,10]. Abdominal Ultrasound (US) and Computed Tomography (CT) scan have high sensitivity for the diagnosis of AI but limited value in discriminating whether a lead point is malignant, benign, or idiopathic [3,10].…”