&lt;p&gt;&lt;strong&gt;Efektivitas wound healing sheet ekstrak Aloe vera dan albumin telur ayam kampung (Gallus domesticus) terhadap penyembuhan luka insisi gingiva&lt;/strong&gt;&lt;/p&gt;&lt;p&gt;&lt;strong&gt;&lt;em&gt;Wound healing sheet with Aloe vera extract and free-range chicken egg albumin (Gallus domesticus) for healing of gingival incisions&lt;/em&gt;&lt;/strong&gt;&lt;/p&gt;

Rosyada, Alya Ghina; A'ziza, Wizni A'dila; Putri, Myrna Evana Amanda; Rochmawati, Mutia

doi:10.24198/pjdrs.v6i2.39927

Cited by 2 publications

(5 citation statements)

References 12 publications

(23 reference statements)

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“…Free-range chicken egg albumin has properties that support cell adhesion as a tissue glue material with active compounds which also promotes wound healing. The combination of wound healing sheets of Aloe vera extract glued using free-range egg albumin makes this material easy to use and has the effect of protecting and accelerating the wound healing process as has been proven in our previous study (5).…”

Section: Discussionmentioning

confidence: 67%

“…Albumin functions in regulating blood osmotic pressure and maintaining water content in blood plasma during the inflammatory phase, therefore, helps to form body tissues in surgical wounds, accelerates tissue healing, and carries away nutrients and oxygen for the formation of new tissue in the proliferative phase (29). Albumin contains natural proteins and collagen that compile the extracellular matrix which induces growth factors, cell migration and adhesion, and tissue regeneration (5). Albumin inhibits the formation of free radicals as a result of phagocytosis of PMN cells and maintains blood osmotic pressure to prevent edema (17).…”

Section: Discussionmentioning

confidence: 99%

“…Currently, alternative non-suturing wound healing methods are developed to address the shortcomings of the suturing method. Synthetic or bio-adhesive tissue glue is one of the alternative methods used (5). Wound closure with tissue glue can be conducted quickly, is relatively painless, has minimal inflammation, easy to remove, and has a lower infection rate than sutures (3).…”

Section: Introductionmentioning

confidence: 99%

“…The results of the study showed a higher number of fibroblasts compared to the natural healing process and suturing treatment after the seventh-day post-application of the preparation. Therefore, it indicates the potential of Aloe vera extracts wound healing sheet combination with free-range chicken egg albumin to accelerate the healing of gingival incision wounds (5).…”

Section: Introductionmentioning

confidence: 99%

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Aloe vera Extract Sheet and Egg Albumin (Gallus domesticus) Reduce the Number of Lymphocytes on Gingival Incision Wound

A'ziza,

Prihastuti,

Rochmawati

et al. 2023

JKB

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An incision in the oral cavity is a dental procedure performed in surgical procedures. Suturing is the gold standard in primary wound closure care, however, suturing can cause tissue trauma, scars, and secondary infections. Cyanoacrylate adhesive is one of the alternative tissue glue for wound closure but it has inflammatory risk as suturing, potential toxicity, and accidental adhesion risks. Aloe vera extract sheet based combined with free-range chicken egg albumin is expected to be an alternative method for wound healing of gingival incisions. This study aimed to investigate the effect of administration of Aloe vera extract wound healing sheet (WHS) and free-range chicken egg albumin on the number of lymphocytes in the gingival incision wound as the inflammatory response. Experimental laboratory research with a posttest-only control group design was conducted in 24 male rats (Rattus norvegicus Wistar strain) with an incised gingiva, divided into four groups, namely T1 (50% WHS concentration and chicken egg albumin), T2 (100% WHS concentration and chicken egg albumin), PC (positive control with suturing), NC (negative control without treatment). The treatment was carried out for seven days. The data obtained were analyzed statistically using One-way ANOVA and Post Hoc LSD. The use of Aloe vera extract WHS and free-range chicken egg albumin (T1 and T2) reduced the number of lymphocytes compared to control groups (PC and NC; p<0.05). WHS and chicken egg albumin can shorten the inflammatory process in wound healing which is characterized by lower lymphocyte counts compared to the control groups.

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Section: Discussionmentioning

confidence: 67%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Aloe vera Extract Sheet and Egg Albumin (Gallus domesticus) Reduce the Number of Lymphocytes on Gingival Incision Wound

A'ziza,

Prihastuti,

Rochmawati

et al. 2023

JKB

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“…The role of albumin is also as a basic ingredient for collagen formation. Collagen is one type of protein that reaches 30% of all proteins that make up the human body [1,22,23].…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of Cork Fish Extract Gel on Fibroblast Proliferation in Socket Wound After Tooth Extraction

HANAFIAH,

SATRIA,

MADHY

et al. 2024

Int J App Pharm

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Objective: Socket wound healing involves soft tissue cells that play an important role, namely fibroblasts. In the wound-healing process, proteins are needed that can accelerate wound healing, one of which is albumin. Cork fish contains the highest albumin than other fish. Albumin contains natural proteins and collagen that make up the extracellular matrix, which has the role of inducing growth factors, cell migration and adhesion, and tissue regeneration. The purpose of this study was to examine the effect of 1%, 3%, 5% and 7% cork fish extract gel on fibroblast cell proliferation in socket wound healing after tooth extraction. Methods: This study was a laboratory experimental study with 30 Wistar rats that were grouped into 5 groups. The treatment group was given cork fish extract gel, namely 1%, 3%, 5% and 7%, and the negative control group was only given base gel was then the tissue was tested using Hematoxylin Eosin to observe fibroblasts on the 3rd, 7th and 14th day. Results: Based on the results of the one-way ANOVA test, it showed that cork fish extract with a concentration of 1%, 3%, 5% and 7% has an effect on fibroblast proliferation in socket wound healing after tooth extraction. Conclusion: Based on the results of the one-way ANOVA test, it showed that 3% cork fish extract had an influence on fibroblast proliferation in healing socket wounds after tooth extraction.

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Cited by 2 publications

References 12 publications

Aloe vera Extract Sheet and Egg Albumin (Gallus domesticus) Reduce the Number of Lymphocytes on Gingival Incision Wound

Aloe vera Extract Sheet and Egg Albumin (Gallus domesticus) Reduce the Number of Lymphocytes on Gingival Incision Wound

Effectiveness of Cork Fish Extract Gel on Fibroblast Proliferation in Socket Wound After Tooth Extraction

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