<p>In vivo Study of Sealing Capability of Raw Propolis Extract and Calcium Hydroxide on Dentin Surface</p>

Abstract

This research aimed to investigate the differences in the sealing capability of propolis extracts and Ca(OH) 2 on dentin surfaces. Materials and Methods: Eighteen mandible incisors of Wistar rats were prepared at a depth of 0.5 mm after which they were randomly divided into 3 groups (n=6) including control (C), pulp-capped with Ca(OH) 2 group (P1), and indirect pulp-capped with propolis extract group (P2). All the cavities were sealed with glass ionomer restorative cement. Moreover, the sections of the teeth were obtained after six Wistar Rats from each group were sacrificed on the second day after treatment. The rats' incisors were cleaved transversally to the area where Ca(OH) 2 and propolis extract bonded with dentin for the SEM (scanning electron microscope) analysis and examined using microphotographs test with 5000x magnification. All the samples were measured and examined with spectrophotometry test to determine the bonding distance between Ca(OH) 2 and dentin, as well as propolis extract and dentin. The result from the two tests was analyzed with SPSS using an independent t-test at p <0.05. Results: There were significant differences between the calcium hydroxide and propolis extract groups (p<0.05) based on the results obtained in the form of spectrums chemical functional groups of spectrophotometry examination. No new chemical bonding or compound was also observed to have been formed between propolis extract with dentin as well as calcium hydroxide with dentin. Conclusion: The adaptation or sealing capability of propolis extract was found to be better than calcium hydroxide to the dentin surface.

The in vitro assessment of rheological properties and dentin remineralization of saliva substitutes containing propolis and aloe vera extracts

“…However, we hypothesize that propolis may promote remineralizing effects via three main mechanisms. Firstly, the resinous propolis extract may form a resinous film or seal on the dentin surface [ 57 ], which may prevent acid penetration and promote mineral deposition of the surface and the saturation of ions on the tooth surface. Furthermore, it was also reported that flavonoids, the commonly found phenolic substance in propolis, could reduce dentin demineralization and promote dentin remineralization via several mechanisms [ 58 ].…”

Bio-based and bio-inspired adhesives from animals and plants for biomedical applications

“…The latter property makes propolis an interesting component for applications in medicine. For instance, it has been used as a film to heal recurrent oral aphthous ulcers [ 166 ], as a coating on dentin to prevent caries [ 167 ], and as an active anti-bacterial component in wound healing scaffolds [ 168 , 169 ]. Moreover, its polyphenol-rich composition provides propolis with antioxidant, antifungal, and antiseptic properties [ 170 ].…”

The Effect of the Combination of Calcium Hydroxide With Green Tea Extract and Calcium Hydroxide With Cacao Peel Extract on the Number of Odontoblast-like Cells and Collagen Type I

“…does not provide long-term good adaptation to dentin, does not support consistent odontoblast differentiation and can cause pulp irritation (5). Furthermore, when calcium hydroxide comes into touch with dentinal fluid, it dissolves the substance and reduces its usefulness, leaving the cavity open and the restoration ineffective (7). The deficiency of calcium hydroxide as a pulp capping material includes possibility of pulp inflammation for more than 3 months and formation of a tunnel defect.…”

“…Calcium hydroxide (Ca (OH)2) is gold standard material for pulp capping. It has alkali properties with pH increased to 12.5 at 37° C for antibacterial (7) and ability to stimulate reparative dentin formation. Calcium hydroxide has the potential to degrade into calcium and hydroxyl ions, stimulating odontoblasts and other pulp cells to create reparative dentin in a variety of ways (4) However, it…”