<p>Familial and Environmental Risk Predisposition in Tonsillectomy: A Case–Control Study</p>

Abstract

Background: Tonsillectomy is one of the most commonly performed procedures among children and it is the gold standard management to reduce episodes of tonsillitis and obstructive symptoms. Many studies showed a significantly higher incidence of previous tonsillectomy in the parents and siblings. This study investigated the influence of familial and environmental trends in tonsillectomy. Methods: Retrospectively, we identified those patients who underwent tonsillectomy (the case group). Also, a control group of participants attending the hospital as visitors who had not undergone tonsillectomy was collected. Both groups are compared using the proper statistical tests. Results: This study included 1,232 participants; 615 underwent tonsillectomy (cases) and 617 did not (controls). It was found that paternal and maternal history of tonsillectomy, childhood asthma, and daycare attendance are independent factors influencing tonsillectomy in the offspring. Of about 85.4% of fathers who underwent tonsillectomy their children will also have tonsillectomy. Also, regarding the maternal history, 72.5% of offspring will have tonsillectomy if the mothers underwent the procedure. Conclusion: This study reveals that genetic predisposition factors may have a role for tonsillectomy and its underlying causative indications. Also, it highlights the importance of asthma control in children. Moreover, the role of ethnicity may be minimal due to the similar trend of this study with other studies. Further studies and prospective research are recommended.

Siblings’ Risk of Adenoid Hypertrophy: A Cohort Study in Children

“…Still, our results confirmed the hypothesis of familial susceptibility to hypertrophy based on endoscopically assessed adenoid size. However, Bani-Ata et al indicated a low significance of tonsillectomy in parental and sibling histories [ 19 ], but the size of palatine tonsils is not the main indication for tonsillectomy; therefore, it is difficult to compare a family predisposition to adenoidectomy with tonsillectomy. However, recurrent or chronic inflammation susceptibility of the adenoids or palatine tonsil tissue may lead to chronic activation of the cell-mediated and humoral immune response, which may play a role in hypertrophy [ 20 ].…”

Comparison Of Diaphragm Thickness Values In Cases of Adenotonsillectomy Before And After The Operation

“…Appraisement of the thickness of the diaphragm with US is a non-invasive, easily accessible method and may guide the patient in anesthesia in terms of extubation timing [4,6]. Adeno-tonsillectomy operations are one of the frequently applied operations in children [8][9][10]. In these cases where intubated and extubated at the end of intervention, it is thought that an objective parameter could be obtained for extubation timing by examining the ratio of the diaphragm muscle thickness to each other in the last inspirum and last exprium before extubation.…”