&lt;p&gt;Complications Following Self-Administration of Hyaluronic Acid Fillers: Literature Review&lt;/p&gt;

Rauso, Raffaele; Nicoletti, Giovanni Francesco; Zerbinati, Nicola; Giudice, Giovanni; Fragola, Romolo; Tartaro, Gianpaolo

doi:10.2147/ccid.s276959

Cited by 5 publications

(9 citation statements)

References 10 publications

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“…Of the total study population, 82.4% were female while 17.6% were male (excluding 1 patient with undisclosed sex). 6 Weighted average age across all studies was 34.5 years (1 study excluded due to insufficient data). 6 All study results are summarized in the Supplemental Digital Content 1 , Table 1, http://links.lww.com/DSS/B326.…”

Section: Resultsmentioning

confidence: 99%

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Complications, Treatment, and Outcomes of Self-Injecting Substances Into the Face: A Systematic Review

Tripathi,

Hakimi,

Parsa

et al. 2023

Dermatol Surg

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BACKGROUND The increased demand for minimally invasive facial cosmetic procedures in tandem with the ease of acquiring injectable cosmetics through direct-to-consumer retailers has led to a rise in self-injecting cosmetics among untrained individuals. OBJECTIVE To analyze complications, treatments, and outcomes associated with self-injecting fillers into the face. METHODS A systematic review of the literature from PubMed and Embase databases was performed from inception to September 10, 2022, to identify studies pertaining to self-injection of facial fillers. RESULTS A total of 15 articles describing 38 complications among 18 patients were included in the data collection. The most commonly injected substance was hyaluronic acid (76.4%). The lips were the most common site of injection (33%). The most reported complication was edema (61%). Severe complications included acute vascular compromise (11%) and acute hearing loss (5%). The most common intervention was use of hyaluronidase and/or antibiotics (87.5%). Patients generally healed after treatment although residual localized hyperpigmentation was noted among 11% of patients. CONCLUSION Injecting commercially available substances into the face is associated with potentially irreversible aesthetic, infectious, and vascular complications, especially in the hands of untrained consumers. Patients and providers should be aware of this dangerous trend.

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Section: Resultsmentioning

confidence: 99%

“…6 Weighted average age across all studies was 34.5 years (1 study excluded due to insufficient data). 6 All study results are summarized in the Supplemental Digital Content 1 , Table 1, http://links.lww.com/DSS/B326.…”

Section: Resultsmentioning

confidence: 99%

Complications, Treatment, and Outcomes of Self-Injecting Substances Into the Face: A Systematic Review

Tripathi,

Hakimi,

Parsa

et al. 2023

Dermatol Surg

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“…Auto-injections of filler materials seem to be an ''underreported phenomenon'' [4], since there are just some case reports available [32][33][34]. Even though the unrecorded cases of auto-injections might be much higher, another potential reason might be the costs for secondary treatment which are not covered by any health insurance.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, other materials are injected as well, e.g., paraffin, silicone, petroleum-jelly-based products, synthol and other fatty agents for skin care, which are freely available in retail. The incorrect and unprofessional use of resorbable and non-resorbable substances, particularly auto-injections by laypeople, have devastating results for patients e.g., tissue breakdown, necrosis and severe inflammation [4]. Auto-injections with exogenous non-medical substances increase these risks dramatically.…”

Section: Introductionmentioning

confidence: 99%

Complications and Disasters After Minimally Invasive Tissue Augmentation with Different Types of Fillers: A Retrospective Analysis

et al. 2021

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Background The interest in youthful appearance and rejuvenating procedures is unbroken in our society. Besides surgical procedures, permanent fillers are utilized. The incorrect and unprofessional use of these substances, auto-injections in particular, have devastating results for patients and are challenging for the plastic surgeon. The aim of this retrospective study was to delineate the differences between permanent and non-permanent filler complications and appropriate treatment options. Methods We conducted a retrospective study and researched the hospital information system in the time period from 2001 to 2020. Patients with unprofessional use of permanent fillers, auto-injections and injections of unformulated substances were determined. Age, gender, localization, complications, length of hospital stay, comorbidities, histopathological workups and surgical salvage procedures were noted. Descriptive statistics were calculated. Results Seventeen patients were identified from 2001 till 2020. In four cases, auto-injections by the patients were the cause, whereas in the other patients the injections were performed by medical staff. Ages range from 18 to 57 years. Fourteen patients were female and three were male. The injected substances could be recognized as synthol, silicone, vaseline, fat tissue, hyaluronic acid as well as non-medical substances. Surgical procedures were necessary in eleven cases. One patient died because of the underlying diseases. Conclusion Our results indicate different sequels of filler materials injected in an unprofessional way, possible complications, conservative and surgical techniques to resolve these rare complications. We suggest a staged therapy adjusted to the clinical symptoms. Milder symptoms can be handled conservatively, whereas severe infections, skin breakdowns or persistent granuloma are justifying indications for surgical treatment. Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

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“…The demand for non-surgical procedures to correct blemishes has grown considerably in recent years, and the injection of hyaluronic acid (HA) represents the second most common procedure after the injection of botulinum toxin, with an increase in demand of 60% from 2014 to 2018 [29]. Hyaluronic acid-based treatments offer a valid alternative to some surgical interventions, with immediate results, little or no recovery times, and the possibility to repeat the procedure if needed [30][31][32].…”

Section: Discussionmentioning

confidence: 99%

Is the Treatment of the Tear Trough Deformity with Hyaluronic Acid Injections a Safe Procedure? A Systematic Review

D'Amato

Fragola

Bove³

et al. 2021

Applied Sciences

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Among the various therapeutic options for the treatment of tear trough deformities, the use of hyaluronic acid-based fillers has constantly been increasing. The aim of this research is to conduct a systematic review of the published literature related to the use of hyaluronic acid-based dermal fillers for the treatment of tear trough deformities and possible related complications. A search of the published literature was conducted following the PRISMA guidelines, including PubMed, Cochrane Library, and Ovid databases. Text words and Medical Search Headings (MeSH terms) were used to identify nine articles included in our analysis. The most used filler was Restylane (Galderma). The injection technique was performed through the use of a cannula or, more frequently, with a needle, through the execution of boluses or retrograde release. The injection plane was predominantly the supra-periosteal layer. The most observed side effects were mild and included redness, edema, contour irregularities, bruising, and blue-gray dyschromia. The degree of patient satisfaction was high, with an optimal aesthetic result that was maintained for 6 to 12 months. Although the duration of treatment of tear trough deformities with HA fillers is not comparable to surgical treatment, this is a minimally invasive, safe procedure, quick to perform, and with a high degree of patient satisfaction.

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<p>Complications Following Self-Administration of Hyaluronic Acid Fillers: Literature Review</p>

Cited by 5 publications

References 10 publications

Complications, Treatment, and Outcomes of Self-Injecting Substances Into the Face: A Systematic Review

Complications, Treatment, and Outcomes of Self-Injecting Substances Into the Face: A Systematic Review

Complications and Disasters After Minimally Invasive Tissue Augmentation with Different Types of Fillers: A Retrospective Analysis

Is the Treatment of the Tear Trough Deformity with Hyaluronic Acid Injections a Safe Procedure? A Systematic Review

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