&lt;p&gt;Comparison of anonymous versus nonanonymous responses to a medication adherence questionnaire in patients with Parkinson&amp;rsquo;s disease&lt;/p&gt;

Prell, Tino; Schaller, Denise; Perner, Caroline; Franke, Gabriele Helga; Witte, Otto W.; Kunze, Anja; Großkreutz, Julian

doi:10.2147/ppa.s186732

Cited by 14 publications

(18 citation statements)

References 17 publications

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“…Information about cognitive state (Montreal Cognitive Assessment (MoCa)) [ 10 ], depressive mood (Beck’s Depression Inventory II (BDI)), motor function (Movement Disorder Society–sponsored revision of the Unified Parkinson’s Disease Rating Scale III (MDS-UPDRS III)) [ 11 ], presence of non-motor symptoms (Revised Non-motor Symptoms Questionnaire (NMS-Q)) [ 12 , 13 ], and adherence to medication (Stendal Adherence with Medication Score; SAMS) was extracted from the medical records. The SAMS includes 18 questions forming a cumulative scale (0–72) in which 0 indicates complete adherence and 72 complete nonadherence [ 14 , 15 ]. The SAMS is available online (CC BY NC 3.0 license; ) [ 16 ].…”

Section: Methodsmentioning

confidence: 99%

Knowledge, Attitudes, Practices, and Burden During the COVID-19 Pandemic in People with Parkinson’s Disease in Germany

Zipprich

Teschner

Witte

et al. 2020

JCM

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Background: Adherence to measures that have been adopted during the COVID-19 pandemic is crucial to control the spread of the coronavirus. Methods: Semi-structured telephone interviews were performed with 99 patients with Parkinson’s disease (PD) and 21 controls to explore knowledge, attitudes, practices, and burden in order to elucidate nonadherence to preventive measures. Results: The majority of patients understood the preventive measures and felt sufficiently informed. Analysis of qualitative answers, however, showed that about 30% of patients had an insufficient level of knowledge, which was not associated with educational level, cognitive disorders, or depression. Changes in behaviour were reported by 73 patients (99% performed at least one specific preventive behavior, and 86.9% have reduced social contacts and stayed home). A closer analysis of qualitative answers showed that 27.3% of patients continued to meet relatives face-to-face almost daily. Anxiety and worries about the current situation were reported by 58.6% of patients; 31.3% complained about a decrease in their mobility since the beginning of the restrictions, mainly because of worsening of PD and because regular therapies (e.g., physiotherapy) were canceled. Conclusions: About 30% of PD patients are nonadherent to preventive measures. Use of simple dichotomous questions overestimates adherence to preventive measures in patients with PD.

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Section: Methodsmentioning

confidence: 99%

Knowledge, Attitudes, Practices, and Burden During the COVID-19 Pandemic in People with Parkinson’s Disease in Germany

Zipprich

Teschner

Witte

et al. 2020

JCM

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“…Adherence was assessed using the German Stendal Adherence to Medication Score (SAMS). The SAMS is based on 18 questions forming a cumulative scale (0–72), in which 0 indicates complete adherence and 72 indicates complete nonadherence [ 11 ]. The SAMS allows the assessment of three common reasons for/clusters of nonadherence: modification of medications, forgetting to take the medications, and missing knowledge about the medications [ 12 ].…”

Section: Methodsmentioning

confidence: 99%

Self-Reported Nonadherence Predicts Changes of Medication after Discharge from Hospital in People with Parkinson’s Disease

Feldmann

Zipprich

Witte

et al. 2020

Parkinson's Disease

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Background. Medication is often changed after hospital discharge in people with Parkinson’s disease (PD). Objective. This observational study aimed to describe changes in PD medication after discharge and explore their association with self-reported adherence and clinical parameters. Methods. During hospitalisation sociodemographic characteristics, the Movement Disorder Society-sponsored revision of the Unified PD Rating Scale for motor function (MDS-UPDRS III), Hoehn and Yahr (H&Y) stage, levodopa equivalent daily dose (LEDD), Beck Depression Inventory II (BDI-II) score, Montreal Cognitive Assessment (MoCA) score, nonmotor symptoms questionnaire (NMSQ), and Stendal Adherence to Medication Score (SAMS) were collected in 125 people with PD. A semistructured interview was conducted 1 month after discharge to determine the extent and reasons for medication changes. Results. Thirty-eight patients (30.4%) changed their PD medication after discharge. Most changes (20.8%) were performed by physicians while 9.6% of patients changed their medication by themselves due to side effects, missing effect of the medication, missing knowledge about the indication, running out of medication, or nonspecific reason. This led to decreased doses while changes by physicians resulted in both increase and decrease of doses as well as new drug prescription. Patients without changes, patients with changes performed by them, and patients with changes performed by physicians did not differ in age, disease duration, MDS-UPDRS III, LEDD, NMSQ, MoCA, BDI-II, gender, marital status, or education. However, patients who themselves made the changes were more likely to be nonadherent according to baseline SAMS. Patients who made changes after discharge had higher SAMS modification and forgetting subscores than patients without changes or with changes made by physicians. Conclusion. Both intended and unintended nonadherence occur in patients who change medication after discharge. The use of an adherence questionnaire during inpatient treatment may help detect patients with higher risk of changing medication after discharge.

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“…This observational study was approved by the local ethics committee of the Jena University Hospital (4572-10/15 (17). It allows the assessments of three common reasons/cluster of nonadherence: modifications of medication, forgetting to take the medication, and lack of knowledge about medications (14).…”

Section: Participants and Assessmentsmentioning

confidence: 99%

What Predicts Different Kinds of Nonadherent Behavior in Elderly People With Parkinson's Disease?

et al. 2020

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Background: Detailed knowledge about nonadherence to medication could improve medical care in elderly patients. We aimed to explore patterns and reasons for nonadherence in people with Parkinson's disease (PD) aged 60 years and older. Methods: Detailed clinical data and adherence (German Stendal Adherence with Medication Score) were assessed in 230 patients with PD (without dementia). Descriptive statistics were used to study reasons for nonadherence in detail, and general linear models were used to study associations between clusters of nonadherence and clinical parameters. Results: Overall, 14.2% (n = 32) of the patients were fully adherent, 66.8% (n = 151) were moderately nonadherent, and 19.0% (n = 43) showed clinically meaningful nonadherence. In the multivariable analysis, nonadherence was associated with a lower education level, higher motor impairment in activities of daily living, higher number of medications per day, and motor complications of PD. Three clusters of nonadherence were observed: 59 (30.4%) patients reported intentional nonadherence by medication modification; in 72 (37.1%) patients, nonadherence was associated with forgetting to take medication; and 63 (32.5%) patients had poor knowledge about the prescribed medication. A lower education level was mainly associated with modification of medication and poorer knowledge about prescribed medication, but not with forgetting to take medication. Patients with motor complications, which frequently occur in those with advanced disease stages, tend to be intentionally nonadherent by modifying their prescribed medication. Increased motor problems and a higher total number of drugs per day were associated with less knowledge about the names, reasons, and dosages of their prescribed medication. Conclusions: Elderly patients with PD report many reasons for intentional and non-intentional nonadherence. Understanding the impact of clinical parameters on different patterns of nonadherence may facilitate tailoring of interventions and counseling to improve outcomes.

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<p>Comparison of anonymous versus nonanonymous responses to a medication adherence questionnaire in patients with Parkinson’s disease</p>

Cited by 14 publications

References 17 publications

Knowledge, Attitudes, Practices, and Burden During the COVID-19 Pandemic in People with Parkinson’s Disease in Germany

Knowledge, Attitudes, Practices, and Burden During the COVID-19 Pandemic in People with Parkinson’s Disease in Germany

Self-Reported Nonadherence Predicts Changes of Medication after Discharge from Hospital in People with Parkinson’s Disease

What Predicts Different Kinds of Nonadherent Behavior in Elderly People With Parkinson's Disease?

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