&lt;p&gt;Comparing the Performance of Charlson and Elixhauser Comorbidity Indices to Predict In-Hospital Mortality Among a Chinese Population&lt;/p&gt;

Cai, Miao; Liu, Echu; Zhang, Ruihua; Lin, Xiaojun; Rigdon, Steven E.; Qian, Zhengmin; BeLue, Rhonda; Chang, Jen Jen

doi:10.2147/clep.s241610

Cited by 41 publications

(29 citation statements)

References 37 publications

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“…Family history of premature or low birth weight newborns and newborn gender were also included. Since the prevalence of each of the following maternal comorbidities was all less than 1%, we created a dichotomous variable for selected maternal comorbidity, with one indicating that the mother has at least one of the following comorbidities: diabetes, thyroid disease, hepatitis, hypertension, heart disease, renal disease, epilepsy, asthma, depression, anxiety, or others [ 28 , 29 ]. Anemia and colporrhagia were included as separate comorbidities since they have higher prevalence (more than 10%).…”

Section: Methodsmentioning

confidence: 99%

Association between maternal outdoor physical exercise and the risk of preterm birth: a case-control study in Wuhan, China

Cai

Zhang

Yang

et al. 2021

BMC Pregnancy Childbirth

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Background China had the second largest proportion of preterm birth (PTB) internationally. However, only 11% of pregnant women in China meet international guidelines for maternal physical activity, a significantly lower proportion than that in Western countries. This study aims to examine the association between outdoor physical exercise during pregnancy and PTB among Chinese women in Wuhan, China. Methods A case-control study was conducted among 6656 pregnant women (2393 cases and 4263 controls) in Wuhan, China from June 2011 to June 2013. Self-reported measures of maternal physical exercise (frequency per week and per day in minutes) were collected. Adjusted odds ratios were estimated using Bayesian hierarchical logistic regression and a generalized additive mixed model (GAMM). Results Compared to women not involved in any physical activity, those who participated in physical exercise 1–2 times, 3–4 times, and over five times per week had 20% (aOR: 0.80, 95% credible interval [95% CI]: 0.68–0.92), 30% (aOR: 0.70, 95% CI: 0.60–0.82), and 32% (aOR: 0.68, 95% CI: 0.59–0.78) lower odds of PTB, respectively. The Bayesian GAMM showed that increasing physical exercise per day was associated with lower risk of PTB when exercise was less than 150 min per day; however, this direction of association is reversed when physical exercise was more than 150 min per day. Conclusion Maternal physical exercise, at a moderate amount and intensity, is associated with lower PTB risk. More data from pregnant women with high participation in physical exercise are needed to confirm the reported U-shape association between the physical exercise and risk of preterm birth.

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Section: Methodsmentioning

confidence: 99%

Association between maternal outdoor physical exercise and the risk of preterm birth: a case-control study in Wuhan, China

Cai

Zhang

Yang

et al. 2021

BMC Pregnancy Childbirth

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“…[20,21]. According to the comorbidity character of our sample, we use Elixhauser Comorbidity Index (contains 31 types of comorbidities) to assess comorbidity, which has been demonstrated to be a more comprehensive and better predictive tool for outcomes of people with cancer [22], and for large Chinese electronic medical record databases [23].…”

Section: Measurementsmentioning

confidence: 99%

Comorbidity in lung cancer patients and its association with hospital readmission and fatality in China

Zhu

Ding

Ma³

et al. 2021

BMC Cancer

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Background Comorbidity has been established as one of the important predictors of poor prognosis in lung cancer. In this study, we analyzed the prevalence of main comorbidities and its association with hospital readmission and fatality for lung cancer patients in China. Methods The analyses are based on China Urban Employees’ Basic Medical insurance (UEBMI) and Urban Residents’ Basic Medical Insurance (URBMI) claims database and Hospital Information System (HIS) Database in the Beijing University Cancer Hospital in 2013–2016. We use Elixhauser Comorbidity Index to identify main types of comorbidities. Results Among 10,175 lung cancer patients, 32.2% had at least one comorbid condition, and the proportion of patients with one, two, and three or more comorbidities was 21.7, 8.3 and 2.2%, respectively. The most prevalent comorbidities identified were other malignancy (7.5%), hypertension (5.4%), pulmonary disease (3.7%), diabetes mellitus (2.5%), cardiovascular disease (2.4%) and liver disease (2.3%). The predicted probability of having comorbidity and the predicted number of comorbidities was higher for middle elderly age groups, and then decreased among patients older than 85 years. Comorbidity was positively associated with increased risk of 31-days readmission and in-hospital death. Conclusion Our study is the first to provide an overview of comorbidity among lung cancer patients in China, underlines the necessity of incorporating comorbidity in the design of screening, treatment and management of lung cancer patients in China.

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“…The 95% CIs were constructed using 1,000 bootstrap replicates with replacement for each model. [28,29] In all statistical analyses, a P value ≤0.05 was considered statistically signi cant. All data cleaning, aggregation, and visualization, and statistical analyses were done using statistical computing environment R (version 4.0.5) [30].…”

Section: Counterfactual Analyses On the Burden Of Alri Attributable To Air Pollutionmentioning

confidence: 99%

Particulate Matter of Different Sizes Associated With Acute Lower Respiratory Infection Outpatient Visits in Children: A Time-Series Analysis in Guangzhou, China

Liang

Meng

Yang

et al. 2021

Preprint

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Background The burden of lower respiratory infection is primarily borne by developing countries. However, the association between particulate matter of different sizes and acute lower respiratory infection (ALRI) outpatient visits in developing countries is less studied. Methods We obtained data on ALRI outpatient visits (N = 105,639) from a tertiary hospital in Guangzhou, China between 2013 and 2019. Over-dispersed generalized additive Poisson models were employed to evaluate the excess risk (ER) associated with particulate matter [inhalable particulate matter (PM10), coarse particulate matter (PMc), and fine particulate matter (PM2.5)]. Counterfactual analyses were used to examine the potential percent reduction of ALRI outpatient visits if the levels of air pollution were as low as those recommended by the World Health Organization (WHO). Results There were 35,310 pneumonia, 68,218 bronchiolitis, and 2,111 asthma outpatient visits included. Each 10 µg/m3 increase of three-day moving averages of particulate matter was associated with significant ER [95% confidence interval (CI)] of outpatient visits of pneumonia [PM2.5: 3.71% (2.91%, 4.52%); PMc: 9.19% (6.94%, 11.49%); PM10: 4.36% (3.21%, 5.52%)], bronchiolitis [PM2.5: 3.21% (2.49%, 3.93%); PMc: 9.13% (7.09%, 11.21%); PM10: 3.12% (2.10%, 4.15%)], and asthma [PM2.5: 3.45% (1.18%, 5.78%); PMc: 11.69% (4.45%, 19.43%); PM10: 3.33% (0.26%, 6.49%)]. The association between particulate matter and pneumonia outpatient visits was stronger among male patients and in cold seasons. Counterfactual analyses suggested that PM2.5 was associated with the largest potential decline of ALRI outpatient visits [pneumonia: 3.89%, 95% CI: (3.24%, 5.52%); bronchiolitis: 4.35% (3.06%, 4.82%); asthma: 5.98% (1.92%, 10.37%)] if the air pollutants were reduced to the level of the reference guidelines. Conclusion Short-term exposure to PM2.5, PMc, and PM10 is associated with significant risk of ALRI outpatient visits, among which PM2.5 is associated with the highest potential decline in outpatient visits if it could be reduced to the WHO recommended level.

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<p>Comparing the Performance of Charlson and Elixhauser Comorbidity Indices to Predict In-Hospital Mortality Among a Chinese Population</p>

Cited by 41 publications

References 37 publications

Association between maternal outdoor physical exercise and the risk of preterm birth: a case-control study in Wuhan, China

Association between maternal outdoor physical exercise and the risk of preterm birth: a case-control study in Wuhan, China

Comorbidity in lung cancer patients and its association with hospital readmission and fatality in China

Particulate Matter of Different Sizes Associated With Acute Lower Respiratory Infection Outpatient Visits in Children: A Time-Series Analysis in Guangzhou, China

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