&lt;p&gt;A Meta-Analysis And Systematic Review Of Accuracy Of Endoscopic Ultrasound For N Staging Of Gastric Cancers&lt;/p&gt;

Chen, Jiafei; Zhou, Changyu; He, Min; Zhen, Zhiming; Wang, Jie; Hu, Xiaofei

doi:10.2147/cmar.s200318

Cited by 15 publications

(14 citation statements)

References 72 publications

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“…EUS is considered the key technique for layer tumor distribution in gastric cancer, which makes it the most important tool for T assessment. On the other hand, CT, due to its wide distribution is the first imaging technique used in many institutions for the assessment of gastric cancer [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Endoscopic Ultrasound vs. Computed Tomography for Gastric Cancer Staging: A Network Meta-Analysis

et al. 2021

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Gastric cancer preoperative staging is of outmost importance to assure proper management of the disease. Providing a relevant clinical stage relies on different imaging methods such as computed tomography (CT) or endoscopic ultrasound (EUS). We aimed to perform a network meta-analysis for gastric cancer clinical stage diagnostic tests, thus comparing the diagnostic accuracy of EUS vs. multidetector CT (MDCT) and EUS vs. EUS + MDCT. We plotted study estimates of pooled sensitivity and specificity on forest plots and summary receiver operating characteristic space to explore between-study variation in the performance of EUS, MDCT and EUS + MDCT for T1–T4, N0–N3, M0–M1 when data were available. Exploratory analyses were undertaken in RevMan 5. We included twelve studies with 2047 patients. Our results suggest that EUS was superior to MDCT in preoperative T1 and N staging. MDCT is more specific for the M stage but no significant difference in sensitivity was obtained. When comparing EUS vs. EUS + MDCT for T1 both sensitivity and specificity were not relevant. No significant differences were observed in T2–T4 stages. Even though EUS helped differentiate between the presence of invaded nodules, N stages should be carefully assessed by both methods since there is not sufficient data.

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Section: Discussionmentioning

confidence: 99%

Endoscopic Ultrasound vs. Computed Tomography for Gastric Cancer Staging: A Network Meta-Analysis

et al. 2021

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“…A recent meta-analysis and systematic review showed that the sensitivity GC N staging using EUS is quite high (82%). But the specificity of EUS for the same N staging in GC was not as high (68%) (67).…”

Section: Gc Stagingmentioning

confidence: 94%

Narrative review of the role of gastroenterologist in the diagnosis, treatment and palliation in gastric and gastroesophageal cancer

2020

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Esophageal cancer (EC) and gastric cancer (GC) carry a high mortality rate. Unfortunately, a majority of patients are asymptomatic and at the time of diagnosis, the disease may invariably be in its advanced stages with limited curative options. Thus, it is imperative to recognize certain risk factors including gastroesophageal reflux disease (GERD), male gender, pre-existing Barrett's esophagus, smoking history, obesity, Helicobacter pylori infection, atrophic gastritis among others for both EC and GC, intervene on time with screening and surveillance modalities if indicated and optimize treatment plans. With advances in endoscopic techniques, early neoplastic lesions are increasingly managed by gastroenterologists, offering an alternative to surgery. The gold standard for diagnosis of EC and GC is high definition endoscopy with adequate targeted biopsies. Endoscopic ultrasound (EUS) is a key in the staging of early cancers dictating the pathway for treatment options. We also play a key role in palliation cases with the aim to reduce the symptoms like nausea, vomiting and even when possible, restore oral intake and improve nutrition in both advanced GC and EC. This review article discusses the risk factors, diagnostic and endoscopic treatment modalities of early EC and GC and palliation of advanced cancer where gastroenterologists play a key role.

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“…After obtaining the histology of the resected specimen, the probability of lymphatic dissemination may much more reliably than by imaging techniques (like conventional EUS[ 133 ]) just be predicted from a nomogram and scoring system derived from >10,000 Patients. [ 95 134 135 136 ] The therapeutic strategy after R0-ER of more advanced superficial cancers is by no means clear or easy.…”

Section: Is There a Role For Eus Miniprobes In N-staging In Early Gastric Cancers?mentioning

confidence: 99%

Controversies in EUS: Do we need miniprobes?

et al. 2021

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This is the fifth in a series of papers entitled “Controversies in EUS.” In the current paper, we deal with high-resolution catheter probes, otherwise known as EUS miniprobes (EUS-MPs). The application of miniprobes for early carcinomas in the entire intestinal tract, for subepithelial lesions, and for findings in the bile duct and pancreatic duct as well as endobronchial use is critically discussed. Submucous lesions, especially in the colon, but also early carcinomas in special cases are considered the most important indications. The argument is illustrated by numerous examples.

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<p>A Meta-Analysis And Systematic Review Of Accuracy Of Endoscopic Ultrasound For N Staging Of Gastric Cancers</p>

Cited by 15 publications

References 72 publications

Endoscopic Ultrasound vs. Computed Tomography for Gastric Cancer Staging: A Network Meta-Analysis

Endoscopic Ultrasound vs. Computed Tomography for Gastric Cancer Staging: A Network Meta-Analysis

Narrative review of the role of gastroenterologist in the diagnosis, treatment and palliation in gastric and gastroesophageal cancer

Controversies in EUS: Do we need miniprobes?

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