&lt;i&gt;Schizonepeta tenuifolia&lt;/i&gt; inhibits collagen stimulated platelet function &lt;i&gt;via&lt;/i&gt; suppressing MAPK and Akt signaling

Jeon, Bo-Ra; Irfan, Muhammad; Kim, Minki; Lee, Seung Eun; Lee, Jeong Hoon; Rhee, Man Hee

doi:10.7555/jbr.32.20180031

Cited by 8 publications

(1 citation statement)

References 34 publications

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“…N. tenuifolia belongs to the Lamiaceae family and has a long history of medicinal use in China, Taiwan, Japan and Korea. N. tenuifolia is used to treat symptoms of common influenza (e.g., fever, headache, virus infections and sore throat) and is supported by pharmacological evidence of anti-inflammatory ( Kim and Chung, 2018 ), immunomodulatory, antioxidative and antipruritic activities ( Lin et al, 2018 ; Jeon et al, 2019 ). The major identified constituents in this substance are (−)-pulegone, (+)-menthone and (+)-limonene.…”

Section: Introductionmentioning

confidence: 99%

Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)

Huang

Lin

2022

Front. Pharmacol.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. As at June 2022, increasing numbers of newly diagnosed COVID-19-associated pneumonia cases worldwide have attracted close attention from the international community. The present review analyzes and summarizes the treatment of COVID-19 with traditional Chinese medicine (TCM). A systematic analysis of the efficacies and benefits of TCM for the treatment of COVID-19 was performed, and the mechanisms underlying such treatment are summarized. This analysis of the literature highlights the potential of TCM to prevent and treat COVID-19 via antiviral, anti-inflammatory and immunomodulatory activities, with evidence showing that many TCM components act upon multiple targets and pathways. Famous TCM formulas include Qing-Fei-Pai-Du-Tang (QFPDT), Lianhuaqingwen Capsule (LHC), Taiwan Chingguan Yihau (NRICM101), and Jing Si herbal drink (JSHD). In particular, the botanical preparation NRICM101 was developed in 2020 for use in viral respiratory tract infections and is recommended for treating non-severe and mild COVID-19 infections. NRICM101 has been adopted for use in Taiwan for the clinical treatment of COVID-19. The common components and active ingredients of 10 TCM preparations have been analyzed for the most promising substances. This review aims to provide reliable evidence demonstrating the therapeutic efficacy of TCM substances in support of their further development against novel coronavirus infectious diseases in Taiwan.

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Section: Introductionmentioning

confidence: 99%

Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)

Huang

Lin

2022

Front. Pharmacol.

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Arbuscular mycorrhizal fungi and production of secondary metabolites in medicinal plants

et al. 2022

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Medicinal plants are an important source of therapeutic compounds used in the treatment of many diseases since ancient times. Interestingly, they form associations with numerous microorganisms developing as endophytes or symbionts in different parts of the plants. Within the soil, arbuscular mycorrhizal fungi (AMF) are the most prevalent symbiotic microorganisms forming associations with more than 70% of vascular plants. In the last decade, a number of studies have reported the positive effects of AMF on improving the production and accumulation of important active compounds in medicinal plants.In this work, we reviewed the literature on the effects of AMF on the production of secondary metabolites in medicinal plants. The major findings are as follows: AMF impact the production of secondary metabolites either directly by increasing plant biomass or indirectly by stimulating secondary metabolite biosynthetic pathways. The magnitude of the impact differs depending on the plant genotype, the AMF strain, and the environmental context (e.g., light, time of harvesting). Different methods of cultivation are used for the production of secondary metabolites by medicinal plants (e.g., greenhouse, aeroponics, hydroponics, in vitro and hairy root cultures) which also are compatible with AMF. In conclusion, the inoculation of medicinal plants with AMF is a real avenue for increasing the quantity and quality of secondary metabolites of pharmacological, medical, and cosmetic interest.

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A review of the botany, traditional uses, phytochemistry and pharmacology of Nepeta tenuifolia Briq.

Shan

Jiang

et al. 2020

Phytochem Rev

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<i>Schizonepeta tenuifolia</i> inhibits collagen stimulated platelet function <i>via</i> suppressing MAPK and Akt signaling

Cited by 8 publications

References 34 publications

Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)

Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)

Arbuscular mycorrhizal fungi and production of secondary metabolites in medicinal plants

A review of the botany, traditional uses, phytochemistry and pharmacology of Nepeta tenuifolia Briq.

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