&lt;i&gt;In vitro&lt;/i&gt; antimicrobial activity of three new generation disinfectants

Eryılmaz, Müjde; Kaşkatepe, Banu; Kiymaci, Merve Eylul; Erol, Hilal Basak; Şimşek, Duygu; Gümüştaş, Ayşen

doi:10.4314/tjpr.v15i10.18

Cited by 5 publications

(5 citation statements)

References 12 publications

(17 reference statements)

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“…Chlorine dioxide has many applications in numerous fields, such as water or wastewater treatment, bleaching, environmental and food disinfection, and sterilization of medical devices. The maximum concentration for chlorine dioxide in the drinking water has been set at 0.8 mg/L by The Environmental Protection Agency (EPA) [3,[17][18][19][20]. Conversely, exposure to higher concentrations might cause serious side effects.…”

Section: Discussionmentioning

confidence: 99%

“…Conversely, exposure to higher concentrations might cause serious side effects. It is a respiratory irritant compound; hence, it may cause irritation of eyes, nose, throat and lungs [18]. Also, the ingestion of these products may cause irritation of the mouth, esophagus and stomach, with severe irritative digestive symptoms; nausea, vomiting and diarrhea, in addition to serious hematological (methemoglobinemia, hemolysis and disseminated intravascular coagulation), cardiovascular and kidney disorders, including renal failure [4,[21][22][23].…”

Section: Discussionmentioning

confidence: 99%

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Intestinal perforation associated with chlorine dioxide ingestion: an adult chronic consumer during COVID-19 pandemic

Arellano-Gutiérrez

Aldana-Zaragoza

Pérez-Fabián

2021

Clin J Gastroenterol

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COVID-19 pandemic is one of the most devastating worldwide crises in recent years. During this pandemic, people have been exposed to products that have not been proven to be safe and effective against COVID-19. We present an adult chronic consumer of chlorine dioxide, in which a fatal outcome is described. This case demonstrates that for people searching products to protect themselves from COVID-19, unregulated access to industrial disinfectants represents a dangerous alternative. To date, there is no scientific evidence to uphold the use of chlorine dioxide or chlorine derivatives as preventive or therapeutic agents against COVID-19. Researchers and general population must take into consideration the fatal possible consequences of not following communications and warnings from health authorities and government institutions.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Intestinal perforation associated with chlorine dioxide ingestion: an adult chronic consumer during COVID-19 pandemic

Arellano-Gutiérrez

Aldana-Zaragoza

Pérez-Fabián

2021

Clin J Gastroenterol

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“…This efficiency was particularly tested on horizontal coupons ( Faure et al, 2016 ). Hydrogen peroxide was selected as disinfectant for its antibacterial and sporicidal activity, and for its surface- and additive-friendly characteristics ( Sagripanti and Bonifacino, 1999 ; Melly et al, 2002 ; Raber and Burklund, 2010 ; Eryilmaz et al, 2016 ). The hydrogen peroxide was known to be neutralized by catalase positive bacteria ( McDonnell and Russell, 1999 ; Pottage et al, 2012 ).…”

Section: Discussionmentioning

confidence: 99%

“…Most studies based on liquid and foam decontamination process were performed between 20 and 24°C (293–297 K) ( Young and Setlow, 2004 ; Ryan et al, 2014 ) or “room temperature” ( Rogers et al, 2005 ; Eryilmaz et al, 2016 ). For certain studies the experimental temperature has not been described ( Andersen et al, 2006 ; Gonzalez et al, 2015 ).…”

Section: Discussionmentioning

confidence: 99%

New Biocide Foam Containing Hydrogen Peroxide for the Decontamination of Vertical Surface Contaminated With Bacillus thuringiensis Spores

Toquin

Faure²,

Orange

et al. 2018

Front. Microbiol.

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Despite scientific advances, bacterial spores remain a major preoccupation in many different fields, such as the hospital, food, and CBRN-E Defense sector. Although many disinfectant technologies exist, there is a lack for the decontamination of difficult to access areas, outdoor sites, or large interior volumes. This study evaluates the decontamination efficiency of an aqueous foam containing hydrogen peroxide, with the efficiency of disinfectant in the liquid form on vertical surfaces contaminated by Bacillus thurengiensis spores. The decontamination efficiency impact of the surfactant and stabilizer agents in the foam and liquid forms was evaluated. No interferences were observed with these two chemical additives. Our results indicate that the decontamination kinetics of both foam and liquid forms are similar. In addition, while the foam form was as efficient as the liquid solution at 4°C, it was even more so at 30°C. The foam decontamination reaction follows the Arrhenius law, which enables the decontamination kinetic to be predicted with the temperature. Moreover, the foam process used via spraying or filling is more attractive due to the generation of lower quantity of liquid effluents. Our findings highlight the greater suitability of foam to decontaminate difficult to access and high volume facilities compared to liquid solutions.

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“…Hydrogen peroxide is an oxidative biocide capable of oxidizing susceptible chemical group and become themselves reduced in the process (Finnegan et al, 2010). The high biocidal concentration causes massive damage to the cells and apoptosis (Eryilmaz et al, 2016).…”

Section: Mechanism Of Hydrogen Peroxidementioning

confidence: 99%

Could antiseptic gargling prevent COVID-19?

2020

Trop Biomed

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<i>In vitro</i> antimicrobial activity of three new generation disinfectants

Cited by 5 publications

References 12 publications

Intestinal perforation associated with chlorine dioxide ingestion: an adult chronic consumer during COVID-19 pandemic

Intestinal perforation associated with chlorine dioxide ingestion: an adult chronic consumer during COVID-19 pandemic

New Biocide Foam Containing Hydrogen Peroxide for the Decontamination of Vertical Surface Contaminated With Bacillus thuringiensis Spores

Could antiseptic gargling prevent COVID-19?

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