<i>In silico</i> evaluation of hypericin and pseudohypericin as candidates for monkeypox treatment
Thai Ke Quan,
Huynh Phuoc,
Hoang Ba Thanh Hai
et al.
Abstract:Monkeypox (Mpox) is a viral zoonotic and human-to-human disease with no specific drug or treatment protocol targeting the monkeypox virus (MPXV). In the MPXV life cycle, viral kinase phosphorylation plays a crucial role in early morphogenesis in the cytoplasm, making inhibition of MPXV kinase a potential therapeutic approach for controlling Mpox. Hypericum sampsonii contains several bioactive compounds, such as hypericin and pseudohypericin, which are known for their antiviral properties. In this study, a comp… Show more
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