<em>Gymnema Sylvestre</em> Supplementation Restores Normoglycemia and Corrects Dyslipidemia through Transcriptional Modulation of ßeta Cells and Hepatocytes in the Alloxan-Induced Hyperglycemic Rats
Abstract:The effect of Gymnema Sylvestre supplementation on beta cell and hepatic activity was explored in an alloxan-induced hyperglycemic rat model. Adult rats were made hyperglycemic via a single inj. (i.p) of Alloxan (120mg/kg b.w). Gymnema Sylvestre was supplemented @250mg/kg and 500mg/kg b.w. Blood glucose levels were constantly monitored. After 21 days, rats were euthanized, and blood and tissues (pancreas and liver) were collected for biochemical, expression, and histological analysis. One-way ANOVA was used to… Show more
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