<![CDATA[<B>Infective valve endocarditis treated by surgery</B>: <B>analysis of 64 cases</B>]]>

Abstract

Objective: To identify some aspects of infective valve endocarditis treated by heart surgery, as well as antibiotic therapy, in a public hospital in the city of Fortaleza, Ceará state, Brazil, from 1988 to 2003. Method: A retrospective and observational study was performed of 64 patients with infective valve endocarditis who required aortic and/or mitral valve replacement, tricuspid vegectomy and repair or pulmonary valve valvulectomy, as well as antibiotic therapy, during their in-hospital stay. They were analyzed in respect to gender, age, time elapsed from hospital admission to the surgery, time elapsed from hospital admission to hospital discharge, valve lesion, blood culture result, surgical treatment and mortality. Results: Infective valve endocarditis treated by heart surgery was more frequent in the third decade of life. Most of patients (81.2%) were males. The patients who died spent a shorter time from hospital admission to the surgery than the patients who survived. The aortic valve was affected in 65% of cases. Positivity blood cultures were seen in 42% and Staphylococcus aureus was isolated in 52.4% of these cases. Valve replacement was necessary in 93.7% of cases. The in-hospital mortality rate was 14.1% which was not influenced by the age of the patient or the blood culture result. Conclusion: Infective valve endocarditis treated by heart surgery was more frequent in men and in the third decade of life. It mostly affected the aortic valve. Staphylococcus aureus was the more common pathogen found. Almost all the patients needed replacement of the infected valve and the in-hospital mortality rate was 14.1%.

Surgical treatment for infective endocarditis and hospital mortality in a Brazilian single-center

“…Still, the hospital mortality in patients with valvular abscess due to complications of IE has been reported as 19.2% in Brazilian patients [23]. Similarly, the present study found a hospital mortality rate of 17% at 30 days for patients undergoing CVS due to IE and prolonged ICU length of stay, probably reflecting the severity of sepsis in these individuals [24][25][26]. However, the anatomical location of the valve infection was similar among the groups, confirming the absence of its association with clinical complications, including mortality, reflecting results previously presented by Rostagno et al [13].…”

Experience of treatment of prosthetic valve endocarditis: a retrospective single-center cross-sectional study

“…This was concordant with previous studies that have mentioned that these valves are the ones predominantly affected by the infectious process. 13 , 17 Mechanical and biological valves were similarly involved, which is also consistent with previous findings. 18 …”

“… 19 Taking into account studies conducted in Brazil, the frequency of negative blood cultures ranges from 40% to 58%. 13 , 15 , 17 , 20 Among these studies, only Pomerantzeff et al 13 specifically evaluated prosthesis endocarditis, and they reported that 50% of the blood cultures were negative (with the limitation of not describing prosthetic valve cultures).…”

Streptococcus bovis endocarditis: analysis of cases between 2005 and 2014

“…5 Two recent Brazilian series of IE with 62 and 64 cases, respectively, did not feature S. bovis as an etiologic agent. 6 , 7 The goal of the present study was to describe the features of a series of cases of IE in a Brazilian scenario, establishing a comparison to what is known from the literature.…”

“…Antibiotic use would rapidly clear S. bovis from the bloodstream, as it is very sensitive to penicillin. 6 , 7 , 19 …”