<b>Efficient vascular and neural engraftment of stem cell-derived islets</b>
Julia Thorngren,
Anja Brboric,
Svitlana Vasylovska
et al.
Abstract:<p dir="ltr">Pluripotent stem cell-derived islets (SC-islets) now emerge as a new source for beta-cell replacement therapy. While the function of human islet transplants is hampered by excessive cell death post-transplantation, contributing factors include inflammatory reactions, insufficient revascularization and islet amyloid formation, there is a gap in knowledge on the engraftment process of the SC-islets. In this experimental study, we investigated the engraftment capability of SC-islets at three mo… Show more
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