LRP8 promotes tumorigenesis in ovarian cancer through inhibiting p53 signaling
Yan Xu,
Yang Zhou,
Xiling Yi
et al.
Abstract:Ovarian cancer (OC) is the most lethal gynecological malignancy with a high mortality rate. Low‐density lipoprotein (LDL) receptor‐related protein 8 (LRP8) is a cell membrane receptor belonging LDL receptor family and is involved in several tumor progressions. However, there is limited understanding of how LRP8 mediates OC development. LRP8 expression level was identified in human OC tissues and cells using immunohistochemical staining and quantitative polymerase chain reaction assays, respectively. Functions … Show more
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