Loxapine-Induced Priapism: A Case Report and Review of the Literature on Antipsychotic-Induced Priapism

Abstract

In this case report, a patient with schizophrenia experienced recurrent priapism while undergoing treatment of acute psychosis. This necessitated a review of the emergent treatment of priapism and discussion of the difficulties in treating priapism in a patient with acute psychosis. Therefore, this case report explores multiple possible etiologies of priapism within the realm of psychiatric care, reviews the proposed mechanisms of medication-induced priapism, and considers the psychopharmacological concepts that pertain to antipsychotic selection in the context of antipsychotic-induced priapism.

Priapism: Current Updates in Clinical Management; Review article Mohammed Raafat Hassan Mohammed

“…For purposes of consistency, the concepts ischemia and non-ischaemia are better over low drainage and high drainage, especially while understanding the penis scanning which follows the treament procedures; this similarly confirms that physicians recognize the importance of interference (2) .…”

The Effectiveness of Priapism's Structured Educational Module on Nurses' Knowledge, Attitude, Beliefs, and Patient’s Profile

“…Despite priapism being a preventable condition, it is a serious and significant problem facing health care systems; increases in the hospital stay and cost negatively affect the patient's impact profile (6) . The condition is classified into three subtypes of priapism; ischemic (generally painful; low flow and veno-occlusive) in record cases, Stuttering (either recurrent or intermittent) considered by repetitive and painful occurrences of extended erections, and non-ischemic (generally non-painful; high arterial flow) (7) . Hematological disorders are the leading cause of priapism, estimated 40% of all the cases, include sickle-cell disease, hyperviscosity syndromes as seen with the myeloproliferative diseases, hypercoagulable states such as deficiencies of proteins C and S, antiphospholipid syndromes, and amyloidosis, while can be precipitated by trauma, neoplasm, neurologic conditions, and pharmacologic substances, e.g., Viagra (6,8) .…”