Lower urinary tract symptoms and depression

Abstract

What ' s known on the subject? and What does the study add? Depression plays an important role in pathogenesis of BPH. Our study shows that prostatic symptoms can be helpful in the screening for depression. OBJECTIVE• To evaluate the relationship between lower urinary tract symptoms (LUTS) and depression in men through validated questionnaires. PATIENTS AND METHODS• Healthy male workers ( n = 673) were invited to a free health check-up.• Patients underwent a detailed medical examination.• All participants completed the International Prostate Symptom Score (IPSS) questionnaire and the Beck Depression Inventory (BDI). RESULTS• Under multiple logistic regression analysis (adjusted for total testosterone and age), a signifi cant effect of IPSS on BDI score was observed: mild depression (BDI score > 9): odds ratio (OR) 1.092, 95% confi dence interval (CI) 1.056 -1.129; P < 0.001; moderate-to-severe depression (BDI score > 19): OR 1.093, 95% CI 1.031 -1.159; P = 0.003; and severe depression (BDI score > 29): OR 1.176, 95% CI 1.048 -1.320; P = 0.006. CONCLUSIONS• In healthy men, LUTS are signifi cantly associated with depression.• The treatment of LUTS is very important for the mental health of older men.

Mental health of Chinese primary care patients with lower urinary tract symptoms

“…In line with previous studies, more severe LUTS symptoms were associated with more severe depressive (Felde et al, 2012;Rom, Schatzl, Swietek, Rucklinger, & Kratzik, 2012;Wong, Woo, Leung, & Leung, 2010) and anxiety symptoms (Felde et al, 2012). The result of regression analysis found that the higher IPSS score of urgency was associated with higher anxiety scores in females.…”

The Influence of Depression, Anxiety and Somatization on the Clinical Symptoms and Treatment Response in Patients with Symptoms of Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia

“…Meanwhile, it was found that the clinical manifestation of LUTS/BPH is strongly associated with psychiatric disturbances such as depression, anxiety, and stress vulnerability, and impairments of instrumental activities during daily living in some studies (5, 10, 11, 12, 13, 14, 15, 16, 17). For instance, the recent large cohort study (14) have also demonstrated the important relationship between LUTS/BPH and depression, in which depression was significantly associated with the severity of the diseases as well as it also involves in all stages of LUTS.…”

“…For instance, the recent large cohort study (14) have also demonstrated the important relationship between LUTS/BPH and depression, in which depression was significantly associated with the severity of the diseases as well as it also involves in all stages of LUTS. According to a large observational, longitudinal, multicenter study (n=666), a substantial proportion (22.6%) of LUTS/BPH patients reported anxiety or depression and they also explained a 7% of variance for explaining the severity of LUTS/BPH.…”

Lower Urinary Tract Symptoms are Associated with Erectile Function and Psychological Symptoms in Men with Late‐Onset Hypogonadism Syndrome

“…Another study indicated that men with moderate to severe LUTS had poorer role functioning, had less energy, and had more depressed and anxious feelings . Furthermore, Rom et al investigated the relationship between LUTS and depression in 673 elderly men through validated questionnaires, and found that LUTS were significantly associated with depression . Disregarding men with LOH or usual elderly people, LUTS may be associated with psychological symptoms.…”