The upper Mesozoic and Cenozoic sedimentary series within about 20 miles on either side of the San Andreas fault has been mapped and systematically classified. Southwest of the fault, the sedimentary series overlies a Mesozoic crystalline basement of plutonic and metamorphic rocks, is from 5,000 to 40,000 feet thick, and is divided into four lithologic sequences. Northeast of the fault, the sedimentary series overlies a Mesozoic basement of eugeosynclinal rocks (Franciscan rocks and serpentine), is from 25,000 to 40,000 feet thick, and is divided into five lithologic sequences. These sequences are in large part separated by regional unconformities. The Cretaceous and Tertiary sequences are marine and terrestrial southwest of the fault, marine northeast of it. The youngest sequence, mainly of Quaternary age, is composed of lithologically similar valley sediments on each side of the fault. Most of the sedimentary sequences are divided into lithologically distinct formations of large areal extent, some of which in turn are divided into local members. A standardized set of names has been designated for the formations and members for this region, using the existing names that are applicable. On opposite sides of the San Andreas fault, not only are the basement rocks contrasting, but the oldest corresponding sedimentary sequences are dissimilar; the successively younger sequences are progressively less different. This condition appears to be the result of persistent right-lateral movement on the fault since Cretaceous time.