Lower sexually transmissible infection prevalence among lifetime exclusive women who have sex with women compared with women who have sex with women and men

Muzny, Christina A.; Kapil, Richa; Austin, Erika L.; Hook, Edward W.; Geisler, William M.

doi:10.1071/sh14181

Cited by 8 publications

(7 citation statements)

References 15 publications

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“…A U.S. population-based survey among women aged 18-59 years demonstrated an HSV-2 seroprevalence of 30% among women reporting same-sex partners during the previous year, 36% among women reporting same-sex partners in their lifetime, and 24% among women reporting no lifetime same-sex behavior (299). HSV-2 seroprevalence among women self-identifying as homosexual or lesbian was 8%, similar to a previous clinic-based study of WSW (299,305) but was 26% among Black WSW in one study (287). The relatively frequent practice of orogenital sex among WSW and WSWM might place them at higher risk for genital infection with HSV-1, a hypothesis supported by the recognized association between HSV-1 seropositivity and previous number of female partners.…”

Section: Women Who Have Sex With Women and Women Who Have Sex With Women And Mensupporting

confidence: 75%

“…Recent studies regarding STI rates among WSW and WSWM indicate that WSWM experience higher rates of STIs than WSW, with rates comparable with women who have sex with men (WSM) in all studies reviewed (279,285,286). These studies indicate that WSW might experience STIs at lower rates than WSWM and WSM, although still at significant rates (287). One study reported higher sexual-risk behaviors among adolescent WSWM and WSW than among adolescent WSM (280).…”

Section: Women Who Have Sex With Women and Women Who Have Sex With Women And Menmentioning

confidence: 97%

See 1 more Smart Citation

Sexually Transmitted Infections Treatment Guidelines, 2021

Workowski¹,

Bachmann²,

Chan³

et al. 2021

MMWR Recomm. Rep.

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These guidelines for the treatment of persons who have or are at risk for sexually transmitted infections (STIs) were updated by CDC after consultation with professionals knowledgeable in the field of STIs who met in Atlanta, Georgia, June 11-14, 2019. The information in this report updates the 2015 guidelines. These guidelines discuss 1) updated recommendations for treatment of Neisseria gonorrhoeae, Chlamydia trachomatis, and Trichomonas vaginalis; 2) addition of metronidazole to the recommended treatment regimen for pelvic inflammatory disease; 3) alternative treatment options for bacterial vaginosis; 4) management of Mycoplasma genitalium; 5) human papillomavirus vaccine recommendations and counseling messages; 6) expanded risk factors for syphilis testing among pregnant women; 7) one-time testing for hepatitis C infection; 8) evaluation of men who have sex with men after sexual assault; and 9) two-step testing for serologic diagnosis of genital herpes simplex virus. Physicians and other health care providers can use these guidelines to assist in prevention and treatment of STIs. BOX 1. The Five P's approach for health care providers obtaining sexual histories: partners, practices, protection from sexually transmitted infections, past history of sexually transmitted infections, and pregnancy intention Additional information about external condoms is available at https://www.cdc.gov/condomeffectiveness. Internal CondomsCondoms for internal vaginal use, also known as female condoms, are available worldwide (e.g., the FC2 Female Condom, Reddy condom, Cupid female condom, and Woman's condom) (31,32). Use of internal condoms can provide protection from acquisition and transmission of STIs, although data are limited. Internal condoms are more costly compared with external condoms; however, they offer the advantage of being controlled by the receptive partner as an STI and HIV prevention method, and the newer versions might be acceptable to all persons. Although the internal condom also has been used during receptive anal intercourse, efficacy associated with this practice remains unknown (33). Additional information about the internal condom is available at http://www.ashasexualhealth. org/pdfs/Male_and_Female_Condoms.pdf. Cervical DiaphragmsIn observational studies, diaphragm use has been demonstrated to protect against cervical gonorrhea, chlamydia, and trichomoniasis (34). However, a trial examining the effect of a diaphragm plus lubricant on HIV acquisition among women in Africa reported no additional protective effect when compared with the use of male condoms alone. Likewise, no difference by study arm in the rate of acquisition of chlamydia, gonorrhea, or herpes occurred (35,36). Diaphragms should not be relied on as the sole source of protection against HIV and other STIs.

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Section: Women Who Have Sex With Women and Women Who Have Sex With Women And Mensupporting

confidence: 75%

Section: Women Who Have Sex With Women and Women Who Have Sex With Women And Menmentioning

confidence: 97%

Sexually Transmitted Infections Treatment Guidelines, 2021

Workowski¹,

Bachmann²,

Chan³

et al. 2021

MMWR Recomm. Rep.

Self Cite

1,606

2,621

View full text Add to dashboard Cite

show abstract

“…Muzny et al 5 did not find any prevalent STIs among 21 lifetime exclusive WSW and only one woman had a history of STIs. This could be explained by the low number of exclusive WSW in the study, but seven women out of the 21 had serological evidence of Chlamydia trachomatis.…”

Section: Discussionmentioning

confidence: 89%

“…Information for these women varies from either that women with female partners are at higher risk for acquiring STIs compared with heterosexual women, to 'As you do not have intercourse you do not need any vaginal examination or routine test' written in a letter from a gynaecologist to a woman with female sexual contacts. Women engaging in same-sex sexual behaviour may be hesitant to seek testing and medical advice concerning sexual health, [1][2][3][4][5] creating challenges in estimating the risk of STIs between females due to small study cohorts. Many of these women also have sex with men, 2,4-10 and the risk of STIs is primarily associated with having male partners.…”

Section: Introductionmentioning

confidence: 99%

Is the risk for sexually transmissible infections (STI) lower among women with exclusively female sexual partners compared with women with male partners? A retrospective study based on attendees at a Norwegian STI clinic from 2004 to 2014

2016

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“…To support the evolution of origin-specific virulence, the transmissibility in women and men and/or the interactions between the sexes must differ (see Figure 5.a and Methods for examples). These biological and social differences are pervasive in human populations: differences between the sexes in infectivity and in susceptibility are ubiquitous 3,6,14,21,23,24,33 ; differences between social groups in their sex-ratios and/or their contact pattern between individuals of the same and the opposite sexes have been widely reported 27,35 .…”

Section: Discussionmentioning

confidence: 99%

Epigenetic inheritance and the evolution of infectious diseases

McLeod

Wild

2020

Preprint

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Genes with identical DNA sequences may show differential expression because of epigenetic marks. These marks in pathogens are key to their virulence and are being evaluated as targets for medical treatment. Where epigenetic marks were created in response to past conditions (epigenetically inherited), they represent a form of memory, the impact of which has not been considered in the evolution of infectious diseases. We fill this gap by exploring the evolution of virulence in pathogens that inherit epigenetic information on the sex of their previous host. We show that memories of past hosts can also provide clues about the sex of present and future hosts when women and men differ in their immunity to infection and/or their interactions with the sexes. These biological and social differences between the sexes are pervasive in humans. We show that natural selection can favour the evolution of greater virulence in infections originating from one sex. Furthermore, natural selection can favour the evolution of greater virulence in infections across sexes (or within sexes). Our results explain certain patterns of virulence in diseases like measles, chickenpox and polio that have puzzled medical researchers for decades. In particular, they address why girls infected by boys (or boys infected by girls) are more likely to die from the infection than girls infected by girls (or boys infected by boys). We propose epigenetic therapies to treat infections by tampering with the memories of infecting pathogens. Counterintuitively, we predict that successful therapies should target pathogen’s genes that inhibit virulence, rather than those enhancing virulence. Our findings imply that pathogens can carry memories of past environments other than sex (e.g. those related to socioeconomic status) that may condition their virulence and could signify an important new direction in personalised medicine.

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Lower sexually transmissible infection prevalence among lifetime exclusive women who have sex with women compared with women who have sex with women and men

Abstract: While lifetime exclusive WSW are at risk of contracting STIs, WSWM are disproportionally affected. Healthcare providers should consider routine STI screening among WSW.

Cited by 8 publications

References 15 publications

Sexually Transmitted Infections Treatment Guidelines, 2021

Sexually Transmitted Infections Treatment Guidelines, 2021

Is the risk for sexually transmissible infections (STI) lower among women with exclusively female sexual partners compared with women with male partners? A retrospective study based on attendees at a Norwegian STI clinic from 2004 to 2014

Epigenetic inheritance and the evolution of infectious diseases

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