Lower risk of peripheral venous catheter-related bloodstream infection by hand insertion

Abstract

Introduction Little is known about the bloodstream infection (BSI) risk associated with short-term peripheral venous catheters (PVCs) and no large study investigated the insertion site-related risk for PVC-BSI. Methods We performed a cohort study at the University of Geneva Hospitals using the prospective hospital-wide BSI surveillance database. We analyzed the association between insertion site and risk of PVC-BSI on the upper extremity using univariable and multivariable marginal Cox models. Results Between 2016 and 2020, utilization of 403′206 peripheral venous catheters were prospectively recorded in a 2000-bed hospital consortium with ten sites. Twenty-seven percent of PVC (n = 109′686) were inserted in the hand. After adjustment for confounding factors, hand insertion was associated with a decreased PVC-BSI risk (adjusted hazard ratio [HR] 0.42, 95% CI 0.18–0.98, p = 0.046) compared to more proximal insertion sites. In a sensitivity analysis for PVCs with ≥ 3 days of dwell time, we confirmed a decreased PVC-BSI risk after hand insertion (HR 0.37, 95% CI 0.15–0.93, p = 0.035). Conclusion Hand insertion should be considered for reducing PVC infections, especially for catheters with an expected dwell time of more than 2 days.

Insertion site and risk of peripheral intravenous catheter colonisation: A post hoc analysis of the CLEAN 3 study including more than 800 catheters

“…These ndings were con rmed by a prospective cohort study involving 400,000 PIVC. In this study, hand insertion reduced the risk of PIVC-related BSI (HR 0.42, 95% CI 0.18-0.98, p = 0.046) compared with proximal insertion sites [9].…”

Insertion site and risk of peripheral intravenous catheter colonization and/or local infection: a post hoc analysis of the CLEAN 3 study including more than 800 catheters

“…Thus, it was not possible to establish a link between insertion site and infectious risk. Finally, in a large prospective cohort study involving more than 400,000 PIVC, hand insertion reduced the risk of PIVC-related BSI (HR [95% CI], 0.42 [0.18–0.98], p = 0.046) compared with proximal insertion sites [ 9 ].…”

Increased Peripheral Venous Catheter Bloodstream Infections during COVID-19 Pandemic, Switzerland

“…Estimates from global device sales illustrated that ≈1.2 billion PVCs are used worldwide annually ( 1 , 2 ). PVC-related complications include phlebitis, hematoma, and extravasation ( 3 , 4 ). PVC-associated bloodstream infections (BSIs) often are disregarded in surveillance systems because of low incidence ( 5 , 6 ).…”