Lower Prevalence than Expected when Screening 70-year-old Men for Abdominal Aortic Aneurysm

Hager, Jakob; Länne, Toste; Carlsson, Per; Lundgren, Fredrik

doi:10.1016/j.ejvs.2013.07.014

Cited by 34 publications

(33 citation statements)

References 39 publications

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“…Four biggest RCTs reported the prevalence of AAA in male populations at the level from 4% to 7.2% [15][16][17][18], however, some recent studies suggested changing epidemiology of AAA. The screening prevalence rates of 1.1-1.7% have been recently reported [9,21]. Our study seems to confirm that trend.…”

Section: Discussionsupporting

confidence: 89%

Prevalence and risk factors of abdominal aortic aneurysm among over 65 years old population in Lublin, Poland

et al. 2019

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Introduction: Abdominal aortic aneurysm (AAA) is a disease exceptionally well suited to screening. Ultrasound-based screening meets all criteria for a screening program according to the WHO, and there is a large evidence supporting its usefulness. Risk factors, mentioned in the available literature, associated with aneurysm formation are advanced age, male gender, tobacco smoking, hypertension, atherosclerotic disease and family or personal history of aortic aneurysms. The aim of the study was to evaluate the incidence of abdominal aortic aneurysms in the population of men and women older than 65 years, in Lublin, Poland and to identify the correlation between risk factors and the AAA incidence. Material and methods: A single-center screening study, for men and women older than 65-years was conducted in Lublin, Poland in May 2018. Patients underwent basic screening ultrasound with measurement of the diameter of abdominal aorta and iliac arteries. Each patient completed anonymous questionnaire to investigate risk factors of developing AAA. Results: 1032 patients, aged 65-91 (median age 71.37) were examined. 569 of them were women and 463 men. 27 aortic aneurysms were detected-7 in a group of women and 20 in a group of men. The total incidence rate of AAA in our study was 2.62%; 1,23% in women and 4,32% in men. Male gender, cigarette smoking, coronary artery disease and a history of myocardial infarction all appeared to be major risk factors of AAA, with relative risk ranging from 2,75 to 4.53. The median diameter of the abdominal aorta was 19.24 mm and varied in groups of patients with different risk factors. Conclusions: The estimated prevalence of AAA in the screened population is within the range of the values reported in previous publications, however, it may confirm a trend of declining prevalence of AAA showed in some recent studies. The presented study confirms the correlation between the AAA and its major risk factors (male sex, smoking cigarettes, coronary artery disease and history of myocardial infarct) as well as a weak association between AAA and hypertension and a negative correlation with diabetes.

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Section: Discussionsupporting

confidence: 89%

Prevalence and risk factors of abdominal aortic aneurysm among over 65 years old population in Lublin, Poland

et al. 2019

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“…The estimate for AAA prevalence of 3·3 per cent, based on 2008–2011, appears to have decreased since the last Danish estimates from a randomized trial in 1994–1998 where it was 4·0 per cent. In a similar Swedish trial a prevalence of 3·4 per cent was recorded for 2008–2010. The prevalence is strongly associated with age.…”

Section: Discussionmentioning

confidence: 88%

Baseline prevalence of abdominal aortic aneurysm, peripheral arterial disease and hypertension in men aged 65–74 years from a population screening study (VIVA trial)

Grøndal

Søgaard

Lindholt

2015

British Journal of Surgery

105

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“…Only 22⋅3 per cent of incident events occurred in men aged 65-74 years ( Table 1), and 13 per cent (8 of 61) of aneurysm-related deaths. Some 33 of the 35 events at age below 75 years occurred in current (24) or previous (9) smokers ( Table 1), with a higher prevalence of current smokers (P < 0⋅001) in patients with acute events than in the underlying study population ( Fig. 3 and Table S1, supporting information).…”

Section: Resultsmentioning

confidence: 96%

Age-specific incidence, risk factors and outcome of acute abdominal aortic aneurysms in a defined population

Howard

Banerjee

Fairhead

et al. 2015

British Journal of Surgery

120

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BackgroundContemporary population‐based data on age‐specific incidence and outcome from acute abdominal aortic aneurysm (AAA) events are needed to understand the impact of risk factor modification and demographic change, and to inform AAA screening policy.MethodsIn a prospective population‐based study (Oxfordshire, UK, 2002–2014), event rates, incidence, early case fatality and long‐term outcome from all acute AAA events were determined, both overall and in relation to the four main risk factors: smoking, hypertension, male sex and age.ResultsOver the 12‐year interval, 103 incident acute AAA events occurred in the study population of 92 728 (men 72·8 per cent; 59·2 per cent 30‐day case fatality rate). The incidence per 100 000 population per year was 55 in men aged 65–74 years, but increased to 112 at age 75–84 years and to 298 at age 85 years or above. Some 66·0 per cent of all events occurred in those aged 75 years or more. The incidence at 65–74 years was highest in male smokers (274 per 100 000 population per year); 27 (96 per cent) of 28 events in men aged less than 75 years occurred in ever‐smokers. Mean(s.d.) age at event was lowest in current smokers (72·2(7·2) years), compared with that in ex‐smokers (81·2(7·0) years) and never‐smokers (83·3(7·9) years) (P < 0·001). Hypertension was the predominant risk factor in women (diagnosed in 93 per cent), with 20 (71 per cent) of all 28 events in women occurring in those aged 75 years or above with hypertension. The 30‐day case fatality rate increased from 40 per cent at age below 75 years to 69 per cent at age 75 years or more (P = 0·008).ConclusionTwo‐thirds of acute AAA events occurred at age 75 years or above, and more than 25 per cent of events were in women. Taken with the strong associations with smoking and hypertension, these findings could have implications for AAA screening.

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Lower Prevalence than Expected when Screening 70-year-old Men for Abdominal Aortic Aneurysm

Abstract: When screening 70-year-old men for AAA, the prevalence was less than half that expected, despite a high attendance rate. Smoking was the strongest risk factor. Almost 40% of the men with AAAs were already known from other means than screening.

Cited by 34 publications

References 39 publications

Prevalence and risk factors of abdominal aortic aneurysm among over 65 years old population in Lublin, Poland

Prevalence and risk factors of abdominal aortic aneurysm among over 65 years old population in Lublin, Poland

Baseline prevalence of abdominal aortic aneurysm, peripheral arterial disease and hypertension in men aged 65–74 years from a population screening study (VIVA trial)

Age-specific incidence, risk factors and outcome of acute abdominal aortic aneurysms in a defined population

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